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発表論文

▶ 2023　　▶ 2022　　▶ 2021　　▶ 2020　　▶ 2019

▶︎ 2018　　▶ 2017　　▶ 2016　　▶︎ 2015　　▶︎ 2014

原著論文

Asano S, Ono A, Sakamoto K, Hayata-Takano A, Nakazawa T, Tanimoto K, Hashimoto H, Ago Y: Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway. Peptides 161: 170940, 2023. (IF: 3.862)

原著論文

Ishida K, Tatsumi K, Minamigawa Y, Mori K, Matsumaru D, Nagase H, Kanda Y, Takuma K, Nakanishi T*: Neuronal differentiation reporter mice as a new methodology for detecting in vivo developmental neurotoxicity. Biochem Pharmacol 206: 115332, 2022. (IF: 6.100)

Asano S, Yamasaka M, Ozasa K, Sakamoto K, Hayata-Takano A, Nakazawa T, Hashimoto H, Waschek JA, Ago Y: Vasoactive intestinal peptide–VIPR2 signaling regulates tumor cell migration. Front Oncol 12: 852358, 2022. (IF: 5.738)

Shintani Y, Hayata-Takano A, Yamano Y, Kuta M, Takeshita R, Takuma K, Okada T, Toyooka N, Takasaki I, Miyata A, Kurihara T, Hashimoto H: Small–molecule non–peptide antagonists of the PACAP receptor attenuate acute restraint stress–induced anxiety–like behaviors in mice. Biochem Biophys Res Commun 631: 146–151, 2022. (IF: 3.322)

Imado E, Sun S, Abawa AR, Tahara T, Kochi T, Huynh TNB, Asano S, Hasebe S, Nakamura Y, Hisaoka–Nakashima K, Kotake Y, Irifune M, Tsuga K, Takuma K, Morioka N, Kiguchi N, Ago Y*: Prenatal exposure to valproic acid causes allodynia associated with spinal microglial activation. Neurochem Int 160: 105415, 2022. (IF: 4.297)

Takemoto T, Baba M, Yokoyama K, Kitagawa K, Nagayasu K, Ago Y, Seiriki K, Hayata-Takano A, Kasai A, Mori D, Ozaki N, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T: Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome. Mol Brain 15: 26, 2022. (IF: 4.399)

原著論文

Yamamoto K, Kuriu T, Matsumura K, Nagayasu K, Tsurusaki Y, Miyake N, Yamamori H, Yasuda Y, Fujimoto M, Fujiwara M, Baba M, Kitagawa K, Takemoto T, Gotoda–Nishimura N, Takada T, Seiriki K, Hayata-Takano A, Kasai A, Ago Y, Kida S, Takuma K, Ono F, Matsumoto N, Hashimoto R, Hashimoto H, Nakazawa T*: Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell–derived neurons from patients with familial schizophrenia. Transl Psychiatry 11: 548, 2021. (IF: 7.989)

Kitagawa K, Matsumura K, Baba M, Kondo M, Takemoto T, Nagayasu K, Ago Y, Seiriki K, Hayata-Takano A, Kasai A, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T: Intranasal oxytocin administration ameliorates social behavioral deficits in a POGZWT/Q1038R mouse model of autism spectrum disorder. Mol Brain 14: 56, 2021. (IF: 4.399)

その他

茂木正樹*, 古屋敷智之, 田熊一敞, 乙黒兼一, 田中智之, 南雅文: ｢COVID–19に対する各大学の対応と生理学及び薬理学教育への影響に関する緊急合同調査｣についての結果報告. 日本薬理学雑誌 156(6): 324–329, 2021.

田熊一敞*: バルプロ酸の胎内曝露による発達障害モデルの作製と新規薬物療法の追究. 子どものこころと脳の発達 12: 26–33, 2021.

原著論文

Kawaguchi C, Shintani N, Hayata-Takano A, Hatanaka M, Kuromi A, Nakamura R, Yamano Y, Shintani Y, Nagai K, Tsuchiya S, Sugimoto Y, Ichikawa A, Okuno Y, Urade Y, Hirai H, Nagata KY, Nakamura M, Narumiya S, Nakazawa T, Kasai A, Ago Y, Takuma K, Baba A, Hashimoto H: Lipocalin–type prostaglandin D synthase regulates light–induced phase advance of the central circadian rhythm in mice. Commun Biol 3: 557, 2020. (IF: 6.584)

Takeuchi S, Kawanai T, Yamauchi R, Chen L, Miyaoka T, Yamada M, Asano S, Hayata-Takano A, Nakazawa T, Yano K, Horiguchi N, Nakagawa S, Takuma K, Waschek JA, Hashimoto H, Ago Y: Activation of the VPAC2 receptor impairs axon outgrowth and decreases dendritic arborization in mouse cortical neurons by a PKA–dependent mechanism. Front Neurosci 14: 521, 2020. (IF: 5.152)

Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, Gotoda–Nishimura N, Igarashi H, Hayashida M, Baba M, Kondo M, Hasebe S, Ueshima K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Iguchi T, Sato M, Yamaguchi S, Tamura M, Wakana S, Yoshiki A, Watabe AM, Okano H, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T: Pathogenic POGZ mutation causes impaired cortical development and reversible autism–like phenotypes. Nat Commun 11: 859, 2020. (IF: 17.694)

Yokoyama R, Higuchi M, Tanabe W, Tsukada S, Naito M, Yamaguchi T, Chen L, Kasai A, Seiriki K, Nakazawa T, Nakagawa S, Hashimoto K, Hashimoto H, Ago Y: (S)–Norketamine and (2S,6S)–hydroxynorketamine exert potent antidepressant–like effects in a chronic corticosterone–induced mouse model of depression. Pharmacol Biochem Behav 191: 172876, 2020. (IF: 3.697)

原著論文

Matsumura K, Baba M, Nagayasu K, Yamamoto K, Kondo M, Kitagawa K, Takemoto T, Seiriki K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Kuriu T, Iguchi T, Sato M, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T: Autism–associated protein kinase D2 regulates embryonic cortical neuron development. Biochem Biophys Res Commun 519(3): 626–632, 2019. (IF: 3.575)

Ago Y*, Tanabe W, Higuchi M, Tsukada S, Tanaka T, Yamaguchi T, Igarashi H, Yokoyama R, Seiriki K, Kasai A, Nakazawa T, Nakagawa S, Hashimoto K, Hashimoto H: (R)–ketamine induces a greater increase in prefrontal 5–HT Release than (S)–ketamine and ketamine metabolites via an AMPA receptor–independent mechanism. Int J Neuropsychopharmacol 22: 665–674, 2019. (IF: 5.176)

Baba M, Yokoyama K, Seiriki K, Naka Y, Matsumura K, Kondo M, Yamamoto K, Hayashida M, Kasai A, Ago Y, Nagayasu K, Hayata-Takano A, Takahashi A, Yamaguchi S, Mori D, Ozaki N, Yamamoto T, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T: Psychiatric–disorder–related behavioral phenotypes and cortical hyperactivity in a mouse model of 3q29 deletion syndrome. Neuropsychopharmacology 44: 2125–2135, 2019. (IF: 7.855)

Seiriki K, Kasai A, Nakazawa T, Niu M, Naka Y, Tanuma M, Igarashi H, Yamaura K, Hayata-Takano A, Ago Y, Hashimoto H: Whole–brain block–face serial microscopy tomography at subcellular resolution using FAST. Nat Protoc 14: 1509–1529, 2019. (IF: 13.491)

Hayata-Takano A, Kamo T, Kijima H, Seiriki K, Ogata K, Ago Y, Nakazawa T, Shintani Y, Higashino K, Nagayasu K, Shintani N, Kasai A, Waschek JA, Hashimoto H: Pituitary Adenylate cyclase–activating polypeptide modulates dendritic spine maturation and morphogenesis via microRNA–132 upregulation. J Neurosci 39: 4208–4220, 2019. (IF: 6.167)

Kawase H, Ago Y, Naito M, Higuchi M, Hara Y, Hasebe S, Tsukada S, Kasai A, Nakazawa T, Mishina T, Kouji H, Takuma K, Hashimoto H: mS–11, a mimetic of the mSin3–binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid–induced autism mouse model. Pharmacol Biochem Behav 176: 1–5, 2019. (IF: 3.697)

総説

Nakazawa T, Hashimoto R, Takuma K, Hashimoto H: Modeling of psychiatric disorders using induced pluripotent stem cell–related technologies. J Pharmacol Sci 140: 321–324, 2019. (IF: 3.337)

原著論文

Shintani Y, Hayata-Takano A, Moriguchi K, Nakazawa T, Ago Y, Kasai A, Seiriki K, Shintani N, Hashimoto H: β–Arrestin1 and 2 differentially regulate PACAP–induced PAC1 receptor signaling and trafficking. PLoS One 13: e0196946, 2018. (IF: 2.740)

Inoue N, Ogura S, Kasai A, Nakazawa T, Ikeda K, Higashi S, Isotani A, Baba K, Mochizuki H, Fujimura H, Ago Y, Hayata-Takano A, Seiriki K, Shintani Y, Shintani N, Hashimoto H: Knockdown of the mitochondria–localized protein p13 protects against experimental parkinsonism. EMBO Rep 19: e44860, 2018. (IF: 7.497)

Inoue N, Hirouchi T, Kasai A, Higashi S, Hiraki N, Tanaka S, Nakazawa T, Nunomura K, Lin B, Omori A, Hayata-Takano A, Kim YJ, Doi T, Baba A, Hashimoto H, Shintani N: Unbiased compound screening with a reporter gene assay highlights the role of p13 in the cardiac cellular stress response. Biochem Biophys Res Commun 495: 1992–1997, 2018. (IF: 2.985)

原著論文

Hara Y, Ago Y, Taruta A, Hasebe S, Kawase H, Tanabe W, Tsukada S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K*: Risperidone and aripiprazole alleviate prenatal valproic acid–induced abnormalities in behaviors and dendritic spine density in mice, Psychopharmacology 234: 3217–3228, 2017. (IF: 3.308)

Hara Y, Ago Y, Higuchi M, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K*: Oxytocin attenuates deficits in social interaction but not recognition memory in a prenatal valproic acid–induced mouse model of autism, Horm Behav 96: 130–136, 2017. (IF: 3.372)

Yamaguchi H, Hara Y, Ago Y, Takano E, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K*: Environmental enrichment attenuates behavioral abnormalities in valproic acid–exposed autism model mice, Behav Brain Res 333: 67–73, 2017. (IF: 3.002)

Hara Y, Ago Y, Takano E, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K*: Prenatal exposure to valproic acid increases miR–132 levels in the mouse embryonic brain, Mol Autism 8: 33, 2017. (IF: 4.833)

Seiriki K, Kasai K, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue K, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Waschek JA, Ago Y, Tanaka KF, Hayata-Takano A, Nagayasu K, Shintani N, Hashimoto R, Kunii Y, Hino M, Matsumoto J, Yabe H, Nagai T, Fujita K, Matsuda T, Takuma K, Baba A, Hashimoto H: High–speed and scalable whole–brain imaging in rodents and primates, Neuron 94: 1085–1100, 2017. (IF: 14.024)

Tanaka T, Ago Y, Umehara C, Imoto E, Hasebe S, Hashimoto H, Takuma K, Matsuda T*: Role of prefrontal serotonergic and dopaminergic systems in encounter–induced hyperactivity in methamphetamine–sensitized mice, Int J Neuropsychopharmacol 20: 410–421, 2017. (IF: 4.712)

Hasebe S, Ago Y, Watabe Y, Oka S, Hiramatsu N, Hashimoto H, Takuma K, Matsuda T*: Anti–anhedonic effect of selective serotonin reuptake inhibitors with affinity for σ1 receptors in the picrotoxin mouse model of anxiety/depression. Br J Pharmacol 174: 314–327, 2017. (IF: 5.491)

Nakazawa T, Kikuchi M, Ishikawa M, Yamamori H, Nagayasu K, Matsumoto T, Fujimoto M, Yasuda Y, Fujiwara M, Okada S, Matsumura K, Kasai A, Hayata-Takano A, Shintani N, Numata S, Takuma K, Akamatsu W, Okano H, Nakaya A, Hashimoto H, Hashimoto R*: Differential gene expression profiles in neurons generated from lymphoblastoid B–cell line–derived iPS cells from monozygotic twin cases with treatment–resistant schizophrenia and discordant responses to clozapine, Schizo Res 181: 75–82, 2017. (IF: 3.986)

総説

Ago Y, Hasebe S, Hiramatsu N, Hashimoto H, TakumaK, MatsudaT*: (2017) Psychopharmacology of combined activation of the serotonin1A and σ1 receptors, Eur J. Pharmacol Sci: in press, 2017. (IF: 2.896)

田熊一敞*, 吾郷由希夫, 長谷部茂, 中澤敬信, 橋本均, 松田敏夫: 幼若期の環境要因による情動行動変化. 日本薬理学雑誌 149: 76–78, 2017.

田熊一敞*, 吾郷由希夫, 原雄大, 長谷部茂, 中澤敬信, 橋本均, 松田敏夫: 発育期環境要因による神経精神疾患発症の制御. 日本生物学的精神医学会誌 28: 22–26, 2017.

原著論文

Morishita Y, Yoshioka Y, Takimura Y, Shimizu Y, Namba Y, Nojiri N, Ishizaka T, Takao K, Yamashita F, Takuma K, Ago Y, Nagano K, Mukai Y, Kamada H, Tsunoda S, Saito S, Matsuda T, Hashida M, Miyakawa T, Higashisaka K, Tsutsumi Y*: Distribution of silver nanoparticles to breast milk and their biological effects on breast–fed offspring mice, ACS Nano 10: 8180–8191, 2016. (IF: 13.334)

Ago Y, Hasebe S, Hiramatsu N, Mori K, Watabe Y, Onaka Y, Hashimoto H, Takuma K, Matsuda T*: Involvement of GABAA receptors in 5–HT1A and σ1 receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency, Psychopharmacology (Berl) 233: 3125–3134, 2016. (IF: 3.540)

Kawanai T, Ago Y, Watanabe R, Inoue A, Taruta A, Onaka Y, Hasebe S, Hashimoto H, Matsuda T, Takuma K*: Prenatal exposure to histone deacetylase inhibitors affects gene expression of autism–related molecules and delays neuronal maturation, Neurochem Res 41: 2574–2584, 2016. (IF: 2.472)

Higashino K, Ago Y, Umeki T, Hasebe S, Onaka Y, Hashimoto H, Takuma K, Matsuda T*: Rivastigmine improves isolation rearing–induced prepulse inhibition deficits via muscarinic acetylcholine receptors in mice, Psychopharmacology (Berl) 233: 521–528, 2016. (IF: 3.540)

Hara Y, Ago Y, Taruta A, Katashiba K, Hasebe S, Takano E, Onaka Y, Hashimoto H, Matsuda T, Takuma K*: Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid–induced autism, Autism Res 9: 926–939, 2016. (IF: 3.048)

Kasai A, Kakihara S, Miura H, Okada R, Hayata-Takano A, Hazama K, Niu M, Shintani N, Nakazawa T, Hashimoto H*: Double in situ hybridization for microRNAs and mRNAs in brain tissues, Frontiers Mol Neurosci 9:126, 2016. (IF: 5.154)

Seiriki K, Kasai A, Kuwaki T, Nakazawa T, Yamaguchi S, Hashimoto H*: Critical involvement of the orbitofrontal cortex in hyperlocomotion induced by NMDA receptor blockade in mice, Biochem Biophys Res Commun 480: 558–563, 2016. (IF: 2.392)

Katano T, Fukuda M, Furue H, Yamazaki M, Abe M, Watanabe M, Nishida K, Yao I, Yamada A, Hata Y, Okumura N, Nakazawa T, Yamamoto T, Sakimura K, Takao T, Ito S*: Involvement of brain–enriched guanylate kinase–associated protein (BEGAIN) in chronic pain after peripheral nerve injury, eNeuro 3: e0110–16, 2016. (IF: ND)

Inoue A, Uchida H, Nakazawa T, Yamamoto T, Ito S*: Phosphorylation of NMDA receptor GluN2B subunit at Tyr1472 is important for trigeminal processing of itch, Eur J Neurosci 44: 2474–2482, 2016. (IF: 2.975).

Onaka Y, Shintani N, Nakazawa T, Kanoh T, Ago Y, Matsuda T, Hashimoto R, Ohi K, Hirai H, Nagata K, Nakamura M, Kasai A, Hayata-Takano A, Nagayasu K, Takuma K, Ogawa A, Baba A, Hashimoto H*: Prostaglandin D2 signaling mediated by the CRTH2 receptor is involved in MK–801–induced cognitive dysfunction, Behav Brain Res 314: 77–86, 2016. (IF: 3.202)

Matsumura K, Nakazawa T*, Nagayasu K, Gotoda–Nishimura N, Kasai A, Hayata-Takano A, Shintani N, Yamamori H, Yasuda Y, Hashimoto R, Hashimoto H: De novo POGZ mutations in sporadic autism disrupt the DNA–binding activity of POGZ, J Mol Psychiatry 4: 1, 2016. (IF: ND)

Nakazawa T, Hashimoto R, Sakoori K, Sugaya Y, Tanimura A, Hashimotodani Y, Ohi K, Yamamori H, Yasuda Y, Umeda–Yano S, Kiyama Y, Konno K, Inoue T, Yokoyama K, Inoue T, Numata S, Ohnuma T, Iwata N, Ozaki N, Hashimoto H, Watanabe M, Manabe T, Yamamoto T, Takeda M, Kano M*: Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders, Nat Commun 7: 10594, 2016. (IF: 11.329)

Hashimoto R, Nakazawa T, Tsurusaki Y, Yasuda Y, Nagayasu K, Matsumura K, Kawasaki H, Yamamori H, Fujimoto M, Ohi K, Umeda–Yano S, Fukunaga M, Fujino H, Kasai A, Hayata-Takano A, Shintani N, Takeda M, Matsumoto N, Hashimoto H: Whole–exome sequencing and neurite outgrowth analysis in autism spectrum disorder, J Hum Genet 61: 199–206, 2016. (IF: 2.487)

総説

吾郷由希夫*, 長谷部茂, 橋本均, 田熊一敞, 松田敏夫: 雌選択性試験：マウス間相互作用を基盤とした新規意欲/報酬探索行動評価系. 日本薬理学雑誌 147: 230–234, 2016.

著書

Ago Y, Takuma K, Matsuda T*: Methamphetamine–induced hyperlocomotion: a focus on the role of the prefrontal serotonergic system. The Neuropathology of drug addictions and substance misuse. Volume 2: Recreational substances/stimulants, club and dissociative drugs, hallucinogens, and inhalants. (Edited by Preedy VR), Elsevier, Amsterdam, Netherlands, 320–328, 2016.

原著論文

Kawanai T, Taruta A, Inoue A, Watanabe R, Ago Y, Hashimoto H, Hasebe S, Ooi Y, Takuma K, Matsuda T*: Decreased expression of hippocampal Na+/Ca2+ exchanger isoform–1 by pentylenetetrazole kindling in mice. Epilepsy Res 115:109–112, 2015. (IF: 2.015)

Ago Y, Hasebe S, Nishiyama S, Oka S, Onaka Y, Hashimoto H, Takuma K, Matsuda T*: The female encounter test: a novel method for evaluating reward–seeking behavior or motivation in mice. Int J Neuropsychopharmacol 18: pyv062, 2015. (IF: 4.009)

Hasebe S, Ago Y, Nishiyama S, Oka S, Hashimoto H, Takuma K, Matsuda T*: Pharmacological profile of encounter–induced hyperactivity in isolation–reared mice. Behav Pharmacol 26: 681–690, 2015. (IF: 2.148)

Hara Y, Takuma K, Takano E, Katashiba K, Taruta A, Higashino K, Hashimoto H, Ago Y, Matsuda T*: Reduced prefrontal dopaminergic activity in valproic acid–treated mouse autism model. Behav Brain Res 289: 39–47, 2015. (IF: 3.028)

Hasebe S, Hiramatsu N, Ago Y, Mori K, Watabe Y, Hashimoto H, Takuma K, Matsuda T*: Role of the 5–HT1A autoreceptor in the enhancement of fluvoxamine–induced increases in prefrontal dopamine release by adrenalectomy/castration in mice. J Pharmacol Sci 127: 232–235, 2015. (IF: 2.360)

Ota Y, Ago Y, Tanaka T, Hasebe S, Toratani Y, Onaka Y, Hashimoto H, Takuma K, Matsuda T*: Anxiolytic–like effects of restraint during the dark cycle in adolescent mice. Behav. Brain Res 284: 103–111, 2015. (IF: 3.028)

総説

田熊一敞, 長谷部茂: 発達環境が神経機能に与える影響. 大阪大学歯学雑誌 60: 21–23, 2015.

原著論文

Ago Y, Tanaka T, Ota Y, Kitamoto M, Imoto E, Takuma K, Matsuda T*: Social crowding in the night–time reduces an anxiety–like behavior and increases social interaction in adolescent mice. Behav Brain Res 270: 37–46, 2014. (IF: 3.391)

Kita Y, Ago Y, Higashino K, Asada K, Takano E, Takuma K, Matsuda T*: Galantamine promotes adult hippocampal neurogenesis via M1 muscarinic and α7 nicotinic receptors in mice. Int J Neuropsychopharmacol 17: 1957–1968, 2014. (IF: 5.264)

Takuma K, Maeda Y, Ago Y, Ishihama T, Takemoto K, Nakagawa A, Shintani N, Hashimoto H, Baba A, Matsuda T*: An enriched environment ameliorates memory impairments in PACAP–deficient mice. Behav Brain Res 272: 269–278, 2014. (IF: 3.391)

Takuma K, Hara Y, Kataoka S, Kawanai T, Maeda Y, Watanabe R, Takano E, Hayata-Takano A, Hashimoto H, Ago Y, Matsuda T*: Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. Pharmacol Biochem Behav 126: 43–49, 2014. (IF: 2.820)

総説

Ago Y. Takuma K, Matsuda T*: The potential role of serotonin1A receptors in post–weaning social isolation–induced abnormal behaviors in rodents. J Pharmacol Sci 125: 237–241, 2014. (IF: 2.114)

▶ 2023 ▶ 2022 ▶ 2021 ▶ 2020 ▶ 2019

▶︎ 2018 ▶ 2017 ▶ 2016 ▶︎ 2015 ▶︎ 2014

原著論文

Asano S*, Ono A, Sakamoto K, Hayata-Takano A, Nakazawa T, Tanimoto K, Hashimoto H, Ago Y*: Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway. Peptides 161: 170940, 2023. (IF: 3.862)

原著論文

Ishida K, Tatsumi K, Minamigawa Y, Mori K, Matsumaru D, Nagase H, Kanda Y, Takuma K, Nakanishi T*: Neuronal differentiation reporter mice as a new methodology for detecting in vivo developmental neurotoxicity. Biochem Pharmacol 206: 115332, 2022. (IF: 6.100)

Asano S*, Yamasaka M, Ozasa K, Sakamoto K, Hayata-Takano A, Nakazawa T, Hashimoto H, Waschek JA, Ago Y*: Vasoactive intestinal peptide–VIPR2 signaling regulates tumor cell migration. Front Oncol 12: 852358, 2022. (IF: 5.738)

Takemoto T, Baba M, Yokoyama K, Kitagawa K, Nagayasu K, Ago Y, Seiriki K, Hayata-Takano A, Kasai A, Mori D, Ozaki N, Takuma K, Hashimoto R, Hashimoto H*, Nakazawa T*: Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome. Mol Brain 15: 26, 2022. (IF: 4.399)

原著論文

その他

茂木 正樹*, 古屋敷 智之, 田熊 一敞, 乙黒 兼一, 田中 智之, 南 雅文: ｢COVID–19に対する各大学の対応と生理学及び薬理学教育への影響に関する緊急合同調査｣についての結果報告. 日本薬理学雑誌 156(6): 324–329, 2021.

田熊 一敞*: バルプロ酸の胎内曝露による発達障害モデルの作製と新規薬物療法の追究. 子どものこころと脳の発達 12: 26–33, 2021.

原著論文

原著論文

Seiriki K, Kasai A*, Nakazawa T, Niu M, Naka Y, Tanuma M, Igarashi H, Yamaura K, Hayata-Takano A, Ago Y, Hashimoto H*: Whole–brain block–face serial microscopy tomography at subcellular resolution using FAST. Nat Protoc 14: 1509–1529, 2019. (IF: 13.491)

総説

Nakazawa T*, Hashimoto R, Takuma K, Hashimoto H*: Modeling of psychiatric disorders using induced pluripotent stem cell–related technologies. J Pharmacol Sci 140: 321–324, 2019. (IF: 3.337)

原著論文

Shintani Y, Hayata-Takano A*, Moriguchi K, Nakazawa T, Ago Y, Kasai A, Seiriki K, Shintani N, Hashimoto H*: β–Arrestin1 and 2 differentially regulate PACAP–induced PAC1 receptor signaling and trafficking. PLoS One 13: e0196946, 2018. (IF: 2.740)

原著論文

Hara Y, Ago Y, Higuchi M, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K*: Oxytocin attenuates deficits in social interaction but not recognition memory in a prenatal valproic acid–induced mouse model of autism, Horm Behav 96: 130–136, 2017. (IF: 3.372)

Yamaguchi H, Hara Y, Ago Y, Takano E, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K*: Environmental enrichment attenuates behavioral abnormalities in valproic acid–exposed autism model mice, Behav Brain Res 333: 67–73, 2017. (IF: 3.002)

Hara Y, Ago Y, Takano E, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K*: Prenatal exposure to valproic acid increases miR–132 levels in the mouse embryonic brain, Mol Autism 8: 33, 2017. (IF: 4.833)

Tanaka T, Ago Y, Umehara C, Imoto E, Hasebe S, Hashimoto H, Takuma K, Matsuda T*: Role of prefrontal serotonergic and dopaminergic systems in encounter–induced hyperactivity in methamphetamine–sensitized mice, Int J Neuropsychopharmacol 20: 410–421, 2017. (IF: 4.712)

Hasebe S, Ago Y, Watabe Y, Oka S, Hiramatsu N, Hashimoto H, Takuma K, Matsuda T*: Anti–anhedonic effect of selective serotonin reuptake inhibitors with affinity for σ1 receptors in the picrotoxin mouse model of anxiety/depression. Br J Pharmacol 174: 314–327, 2017. (IF: 5.491)

総説

Ago Y, Hasebe S, Hiramatsu N, Hashimoto H, TakumaK, MatsudaT*: (2017) Psychopharmacology of combined activation of the serotonin1A and σ1 receptors, Eur J. Pharmacol Sci: in press, 2017. (IF: 2.896)

田熊 一敞*, 吾郷 由希夫, 長谷部 茂, 中澤 敬信, 橋本 均, 松田 敏夫: 幼若期の環境要因による情動行動変化. 日本薬理学雑誌 149: 76–78, 2017.

田熊 一敞*, 吾郷 由希夫, 原 雄大, 長谷部 茂, 中澤 敬信, 橋本 均, 松田 敏夫: 発育期環境要因による神経精神疾患発症の制御. 日本生物学的精神医学会誌 28: 22–26, 2017.

原著論文

Kawanai T, Ago Y, Watanabe R, Inoue A, Taruta A, Onaka Y, Hasebe S, Hashimoto H, Matsuda T, Takuma K*: Prenatal exposure to histone deacetylase inhibitors affects gene expression of autism–related molecules and delays neuronal maturation, Neurochem Res 41: 2574–2584, 2016. (IF: 2.472)

Higashino K, Ago Y, Umeki T, Hasebe S, Onaka Y, Hashimoto H, Takuma K, Matsuda T*: Rivastigmine improves isolation rearing–induced prepulse inhibition deficits via muscarinic acetylcholine receptors in mice, Psychopharmacology (Berl) 233: 521–528, 2016. (IF: 3.540)

Kasai A, Kakihara S, Miura H, Okada R, Hayata-Takano A, Hazama K, Niu M, Shintani N, Nakazawa T, Hashimoto H*: Double in situ hybridization for microRNAs and mRNAs in brain tissues, Frontiers Mol Neurosci 9:126, 2016. (IF: 5.154)

Seiriki K, Kasai A, Kuwaki T, Nakazawa T, Yamaguchi S, Hashimoto H*: Critical involvement of the orbitofrontal cortex in hyperlocomotion induced by NMDA receptor blockade in mice, Biochem Biophys Res Commun 480: 558–563, 2016. (IF: 2.392)

Inoue A, Uchida H, Nakazawa T, Yamamoto T, Ito S*: Phosphorylation of NMDA receptor GluN2B subunit at Tyr1472 is important for trigeminal processing of itch, Eur J Neurosci 44: 2474–2482, 2016. (IF: 2.975).

Matsumura K, Nakazawa T*, Nagayasu K, Gotoda–Nishimura N, Kasai A, Hayata-Takano A, Shintani N, Yamamori H, Yasuda Y, Hashimoto R, Hashimoto H: De novo POGZ mutations in sporadic autism disrupt the DNA–binding activity of POGZ, J Mol Psychiatry 4: 1, 2016. (IF: ND)

総説

吾郷 由希夫*, 長谷部 茂, 橋本 均, 田熊 一敞, 松田 敏夫: 雌選択性試験：マウス間相互作用を基盤とした新規意欲/報酬探索行動評価系. 日本薬理学雑誌 147: 230–234, 2016.

著書

原著論文

Kawanai T, Taruta A, Inoue A, Watanabe R, Ago Y, Hashimoto H, Hasebe S, Ooi Y, Takuma K, Matsuda T*: Decreased expression of hippocampal Na+/Ca2+ exchanger isoform–1 by pentylenetetrazole kindling in mice. Epilepsy Res 115:109–112, 2015. (IF: 2.015)

Ago Y, Hasebe S, Nishiyama S, Oka S, Onaka Y, Hashimoto H, Takuma K, Matsuda T*: The female encounter test: a novel method for evaluating reward–seeking behavior or motivation in mice. Int J Neuropsychopharmacol 18: pyv062, 2015. (IF: 4.009)

Hasebe S, Ago Y, Nishiyama S, Oka S, Hashimoto H, Takuma K, Matsuda T*: Pharmacological profile of encounter–induced hyperactivity in isolation–reared mice. Behav Pharmacol 26: 681–690, 2015. (IF: 2.148)

Hara Y, Takuma K, Takano E, Katashiba K, Taruta A, Higashino K, Hashimoto H, Ago Y, Matsuda T*: Reduced prefrontal dopaminergic activity in valproic acid–treated mouse autism model. Behav Brain Res 289: 39–47, 2015. (IF: 3.028)

Hasebe S, Hiramatsu N, Ago Y, Mori K, Watabe Y, Hashimoto H, Takuma K, Matsuda T*: Role of the 5–HT1A autoreceptor in the enhancement of fluvoxamine–induced increases in prefrontal dopamine release by adrenalectomy/castration in mice. J Pharmacol Sci 127: 232–235, 2015. (IF: 2.360)

Ota Y, Ago Y, Tanaka T, Hasebe S, Toratani Y, Onaka Y, Hashimoto H, Takuma K, Matsuda T*: Anxiolytic–like effects of restraint during the dark cycle in adolescent mice. Behav. Brain Res 284: 103–111, 2015. (IF: 3.028)

総説

田熊 一敞, 長谷部 茂: 発達環境が神経機能に与える影響. 大阪大学歯学雑誌 60: 21–23, 2015.

原著論文

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▶︎ 2018　　▶ 2017　　▶ 2016　　▶︎ 2015　　▶︎ 2014

Asano S, Ono A, Sakamoto K, Hayata-Takano A, Nakazawa T, Tanimoto K, Hashimoto H, Ago Y: Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway. Peptides 161: 170940, 2023. (IF: 3.862)

Asano S, Yamasaka M, Ozasa K, Sakamoto K, Hayata-Takano A, Nakazawa T, Hashimoto H, Waschek JA, Ago Y: Vasoactive intestinal peptide–VIPR2 signaling regulates tumor cell migration. Front Oncol 12: 852358, 2022. (IF: 5.738)

Takemoto T, Baba M, Yokoyama K, Kitagawa K, Nagayasu K, Ago Y, Seiriki K, Hayata-Takano A, Kasai A, Mori D, Ozaki N, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T: Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome. Mol Brain 15: 26, 2022. (IF: 4.399)

茂木正樹*, 古屋敷智之, 田熊一敞, 乙黒兼一, 田中智之, 南雅文: ｢COVID–19に対する各大学の対応と生理学及び薬理学教育への影響に関する緊急合同調査｣についての結果報告. 日本薬理学雑誌 156(6): 324–329, 2021.

田熊一敞*: バルプロ酸の胎内曝露による発達障害モデルの作製と新規薬物療法の追究. 子どものこころと脳の発達 12: 26–33, 2021.

Seiriki K, Kasai A, Nakazawa T, Niu M, Naka Y, Tanuma M, Igarashi H, Yamaura K, Hayata-Takano A, Ago Y, Hashimoto H: Whole–brain block–face serial microscopy tomography at subcellular resolution using FAST. Nat Protoc 14: 1509–1529, 2019. (IF: 13.491)

Nakazawa T, Hashimoto R, Takuma K, Hashimoto H: Modeling of psychiatric disorders using induced pluripotent stem cell–related technologies. J Pharmacol Sci 140: 321–324, 2019. (IF: 3.337)

Shintani Y, Hayata-Takano A, Moriguchi K, Nakazawa T, Ago Y, Kasai A, Seiriki K, Shintani N, Hashimoto H: β–Arrestin1 and 2 differentially regulate PACAP–induced PAC1 receptor signaling and trafficking. PLoS One 13: e0196946, 2018. (IF: 2.740)

田熊一敞*, 吾郷由希夫, 長谷部茂, 中澤敬信, 橋本均, 松田敏夫: 幼若期の環境要因による情動行動変化. 日本薬理学雑誌 149: 76–78, 2017.

田熊一敞*, 吾郷由希夫, 原雄大, 長谷部茂, 中澤敬信, 橋本均, 松田敏夫: 発育期環境要因による神経精神疾患発症の制御. 日本生物学的精神医学会誌 28: 22–26, 2017.

吾郷由希夫*, 長谷部茂, 橋本均, 田熊一敞, 松田敏夫: 雌選択性試験：マウス間相互作用を基盤とした新規意欲/報酬探索行動評価系. 日本薬理学雑誌 147: 230–234, 2016.

田熊一敞, 長谷部茂: 発達環境が神経機能に与える影響. 大阪大学歯学雑誌 60: 21–23, 2015.