Department of Oral Physiology,
Osaka University Graduate School of Dentistry

Graduate School of Dentistry

JAPANESE

Welcome to Kato's Lab

Message

Oral physiology plays an important role as a discipline that forms the basis of dental care for stomatognathic diseases and dysfunction. The orofacial system, such as chewing, swallowing and speaking plays critical roles in health. However, its mechanisms are complicated and still largely unknown. We are studying mechanisms underlying the normal and abnormal orofacial functions at levels from molecules to whole animals or human subjects by using both in vivo and in vitro neurophysiological techniques. We aim to transfer research results to clinical applications such as development of new preventive and therapeutic methods.

Staff
Professor Takafumi KATO kato.takafumi.dent*
Associate Professor Hiroki TOYODA toyoda.hiroki.dent*
Associate Professor Ayano KATAGIRI katagiri.ayano.dent*

* Please add the domain name "@osaka-u.ac.jp" to these IDs.

Our current research projects

①Neurophysiology of mastication and sleep-related teeth grinding

Sleep bruxism is a common sleep related disorder characterized by the frequent occurrence of tooth grinding during sleep. However, patients with sleep bruxism do not exhibit abnormalities in indispensable oral functions for survival such as swallowing and chewing. Therefore, we are studying the neurophysiological substrates contributing the discrepant roles of masticatory motor system during sleep and wakefulness in animal models. We also conducting polysomnographic study in humans to understand the physiology of oromotor activity during sleep.

②Mechanism of a vicious cycle between oral sensorimotor functions and sleep problems

The patients with chronic pain often fall into a vicious cycle with sleep disturbance; the decrease in sleep quality worsens pain symptoms, and vice versa. We are trying to clarify the roles of chronic intermittent hypoxia, i.e., sleep apnea, on the development of pain-sleep interaction in animal model by using behavioral, pharmacological, immunohistochemical and electrophysiological techniques.
Sleep plays significant roles in development. We are investigating the influences of sleep disturbance on behavioral, electromyographic and neurobiological aspects of ingestive behavior in experimental animals and in human children.

③Information processing mechanisms of oral sensations　

The recognition of oral sensations results from the integration of various sensory information, such as taste, olfaction and somatosensory sensations. In this study, we are studying the effects of taste, olfactory and somatosensory disorders on the integration of various sensory information in animals using behavioral, immunohistochemical, electrophysiological and optical imaging techniques to understand the information processing mechanisms of oral sensations.

④The mechanisms underlying taste and olfactory impairments

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the degeneration of dopaminergic neurons in the brain. Taste or olfactory impairments are common findings in PD patients. However, the underlying pathophysiology of PD-related taste or olfactory impairments remain poorly understood. We are investigating the taste and olfactory function in toxin-induced PD model animals using behavioral, immunohistochemical and electrophysiological techniques.

⑤Challenge for sleep database

Recently, an interest on sleep health is growing in the society and SleepTech has been emerged for developing sleep-promoting technologies. We are accumulating the polysomnographic data in humans to establish Japanese sleep database for applying medical and information engineering.

Recent publications:

2024

Original papers

  • Ikeda M, Mochizuki A, Kato T, Nakamura S, Nakayama K, Dantsuji M, Baba K, Inoue T. Fluoxetine, but not paroxetine, alters the jaw-closing muscle activity during non-rapid eye movement sleep in mice. Neuroscience Research, doi: 10.1016/j.neures.2024.09.004. Online ahead of print.
  • Katagiri A, Kishimoto S, Okamoto Y, Yamada M, Niwa H, Bereiter DA, Kato T. Effect of chronic intermittent hypoxia on ocular and intraoral mechanical allodynia mediated via the calcitonin gene-related peptide in a rat. Sleep. 2024 Mar 11;47(3):zsad332. doi: 10.1093/sleep/zsad332.
  • Katagiri A, Yamada M, Sato H, Toyoda H, Niwa H, Kato T. Long-lasting adverse effects of short-term stress during the suckling-mastication transition period on masticatory function and intraoral sensation in rats. Odontology. 2024 Jan 10. doi: 10.1007/s10266-023-00887-w. Online ahead of print.
  • Higashiyama M, Masuda Y, Katagiri A, Toyoda H, Yamada M, Yoshida A, Kato T. Rhythmic jaw muscle activity induced by electrical stimulation of the corticobulbar tract during rapid eye movement sleep in comparison to wakefulness and non-rapid eye movement sleep in freely moving guinea pigs. Journal of Oral Biosciences,
    https://doi.org/10.1016/j.job.2024.09.004.

Reviews

  • Ono T, UenoT, Kido M, Hitomi S, Naniwa M, Nakatomi C, Ushimoto R, Sawada T, Kato T. Recent advances in the treatment of oral ulcerative mucositis from clinical and basic perspectives. J Oral Biosciences; 66:504-510, 2024.
    https://doi.org/10.1016/j.job.2024.06.002

2023

Original papers

  • Yamada M, Katagiri A, Masuda Y, Toyoda H, Niwa H, Kato T. Longitudinal electromyographic analysis of jaw-closing muscle activities during ingestive behaviors from pre-weaning to juvenile periods in rats. Physiol Behav. 2023 Jun 1;265:114173. doi: 10.1016/j.physbeh.2023.114173.
  • Haraki S, Tsujisaka A, Shiraishi Y, Toyota R, Katagiri A, Toyoda H, Ishigaki S, Taniike M, Kato T. Reciprocal first night effect on rhythmic and non-rhythmic oromotor episodes in moderate to severe primary sleep bruxism: A retrospective physiological study. J Oral Rehabil. 2023 Apr 19. doi: 10.1111/joor.13474. Online ahead of print.
  • Okura M, Kato T, Mashita M, Muraki H, Sugita H, Ohi M, Taniguchi M. Relationships between respiratory and oromotor events differ between motor phenotypes in patients with obstructive sleep apnea. Front Neurol. 2023;14:1150477. doi: 10.3389/fneur.2023.1150477. eCollection 2023.
  • Toyoda H, Fujinami Y, Saito M, Maeda Y, Kang Y. Increased vertical dimension of occlusion for varying periods differentially impairs learning and memory in guinea pigs. Behav Brain Res. 2023 Jun 16;452:114547. doi: 10.1016/j.bbr.2023.114547. Online ahead of print.
  • Katagiri A, Tsubota K, Mikuzuki Lou, Nakamura S, Toyofuku A, Kato T, Bereiter DA, Iwata K. Diquafosol sodium reduces neuronal activity in trigeminal subnucleus caudalis in a rat model of chronic dry eye disease. Neurosci Lett. 2023; 792: 136939.
    https://doi.org/10.1016/j.neulet.2022.136939
  • Katagiri A, Tsubota K, Mikuzuki Lou, Nakamura S, Toyofuku A, Kato T, Bereiter DA, Iwata K. Tear secretion by Diquafosol suppresses the excitability of trigeminal brainstem nuclear complex neurons by reducing excessive P2Y2 expression in the trigeminal ganglion in dry eye rats. Neurosci Res. 2023 Jun; 191: 66-76. doi: 10.1016/j.neures.2023.01.003.
  • Huang Z, Zhou N, Lobbezoo F, Almeida FR, Cistulli PA, Dieltjens M, Huynh NT, Kato T, Lavigne GJ, Masse JF, Pliska BT, van de Rijt L, Sutherland K, Thymi M, Vanderveken OM, de Vries R, Aarab G. Dental sleep-related conditions and the role of oral healthcare providers: A scoping review. Sleep Med Rev. 2023 Feb;67:101721. doi: 10.1016/j.smrv.2022.101721. Epub 2022 Nov 19.
  • Manfredini D, Ahlberg J, Aarab G, Bender S, Bracci A, Cistulli PA, Conti PC, De Leeuw R, Durham J, Emodi-Perlman A, Ettlin D, Gallo LM, Häggman-Henrikson B, Hublin C, Kato T, Klasser G, Koutris M, Lavigne GJ, Paesani D, Peroz I, Svensson P, Wetselaar P, Lobbezoo F. Standardized Tool for the Assessment of Bruxism (STAB). J Oral Rehabil. 2023 Jan 3. doi: 10.1111/joor.13411. Epub ahead of print.
  • Dal Fabbro C, Rompré P, Kato T, Maluly M, Haraki S, Toyota R, Shiraishi Y, Andersen ML, Tufik S, Montplaisir J, Herrero Babiloni A, Lavigne GJ. The influence of age on the frequency of rhythmic masticatory muscle activity during sleep in general population differs from that in clinical research samples. J Oral Rehabil. 2023 Jan;50(1):54-61. doi: 10.1111/joor.13388. Epub 2022 Nov 21.
  • Abe S, Huynh NT, Rompré PH, de Grandmont P, Landry-Schönbeck A, Landry ML, Kato T, Kawano F, Lavigne GJ. Sleep Quality and Comfort Reported by Sleep Bruxism Individuals Wearing the Occlusal Splint and Mandibular Advancement Splint: Revisiting Two Crossover Studies. Int J Prosthodont. 2022 Dec 6. doi: 10.11607/ijp.7525. Epub ahead of print.
  • Saito M, Tanaka C, Toyoda H, Kang Y. Subcellular Localization of Homomeric TASK3 Channels and Its Presumed Functional Significances in Trigeminal Motoneurons. Int J Mol Sci. 2022 Dec 25;24(1):344. doi: 10.3390/ijms24010344.
  • Tanaka Y, Sato H, Toyoda H, Saito M, Maeda Y, Kang Y. The mechanism for regulating the isometric contraction of masseter muscles is involved in determining the vertical dimension of occlusion. J Neurophysiol. 129(1): 211-219, 2023. doi: 10.1152/jn.00301.2022.

Reviews

  • Zhu Y, Toyota R, Shiraishi Y, Katagiri A, Yamada M, Higashiyama M, Toyoda H, Lavigne G, Kato T. Sleep architecture as a candidate for phenotyping sleep bruxism: A narrative physiological review. J Oral Rehabil. 2023 Apr 28. doi: 10.1111/joor.13482. Online ahead of print.
  • Kato T, Higashiyama M, Katagiri A, Toyoda H, Yamada M, Minota N, Katsura-Fuchihata S, Zhu Y. Understanding the pathophysiology of sleep bruxism based on human and animal studies: A narrative review. J Oral Biosci. 2023 Apr 20:S1349-0079(23)00051-8. doi: 10.1016/j.job.2023.04.005. Online ahead of print.

2022

Original papers

  • Shimoda M, Toyoda H, Sato H, Katagiri A, Yamada M, Murakami J, Akiyama S, Kato T. Long-term changes in oral feeding behaviors of growing rats. Odontology. doi: 10.1007/s10266-022-00739-z.
  • Tsutsumi Y, Sato F, Furuta T, Uchino K, Moritani M, Bae YC, Kato T, Tachibana Y, Yoshida A. The Cerebellar Cortex Receives Orofacial Proprioceptive Signals from the Supratrigeminal Nucleus via the Mossy Fiber Pathway in Rats. The Cerebellum, 2022. doi: 10.1007/s12311-022-01434-z.
  • Abe S, Huynh N, Kato T, Rompre PH, Landry-Schonbeck A, Landry M, de Grandmont P, Kawano F, Lavigne GJ. Oral appliances reduce masticatory muscle activity-sleep bruxism metrics independently of changes in heart rate variability. Clinical Oral Investigations. 26(9): 5653-5662, 2022. doi: 10.1007/s00784-022-04520-y.
  • Yin DX, Toyoda H, Nozaki K, Satoh K, Katagiri A, Adachi K, Kato T, Sato H. Taste Impairments in a Parkinson’s Disease Model Featuring Intranasal Rotenone Administration in Mice. Journal of Parkinson's Disease. 12: 1863-1880, 2022. doi: 10.3233/JPD-223273.
  • Toyoda H, Won J, Kim W, Kim D, Davy O, Saito M, Kim D, Tanaka T, Kang Y, Oh SB. The Nature of Noradrenergic Volume Transmission From Locus Coeruleus to Brainstem Mesencephalic Trigeminal Sensory Neurons. Front Cell Neurosci. 16: 841239, 2022. doi: 10.3389/fncel.2022.841239.
  • Yano H, Ueno Y, Higashiyama M, Akhter F, Katagiri A, Toyoｄa H, Uzawa N, Yoshida A, Kato T. After-effects of acute footshock stress on sleep states and rhythmic masticatory muscle activity during sleep in guinea pigs. Odontology. 110(3): 476-481, 2022.
    https://doi.org/10.1007/s10266-021-00679-0
  • Motor representation of rhythmic jaw movements in the amygdala of guinea pigs. Ueno Y, Higashiyama M, Haque T, Masuda Y, Katagiri A, Toyoda H, Uzawa N, Yoshida A, Kato T. Archives of Oral Biology. 135: 105362, 2022.[Open access]
  • Sasaki Y, Otsugu M, Sasaki H, Fujikawa N, Okawa R, Kato T, Nakano K. Relationship between dental occlusion and maximum tongue pressure in preschool children aged 4 -6 years. Children. 9(2): 141, 2022. [Open access]
  • Kishimoto S, Katagiri A, Oyamaguchi A, Sato H, Toyoda H, Niwa H, Bereiter DA, Iwata K, Kato T. Enhanced Ocular Surface and Intraoral Nociception via a Transient Receptor Potential Vanilloid 1 Mechanism in a Rat Model of Obstructive Sleep Apnea. Neuroscience. 483: 66-81, 2022. [Open access]
  • Toyota R, Fukui K, Kamimura M, Katagiri A, Sato H, Toyoda H, Rompre P, Ikebe K, Kato T. Sleep stage-dependent changes in tonic masseter and cortical activities in young subjects with primary sleep bruxism. Sleep. 45(4): zsab207, 2022. doi: 10.1093/sleep/zsab207.
  • Toyoda H, Koga K. Nicotine Exposure during Adolescence Leads to Changes of Synaptic Plasticity and Intrinsic Excitability of Mice Insular Pyramidal Cells at Later Life. Int J Mol Sci. 23(1): 34, 2022. doi: 10.3390/ijms23010034.
  • Nishibe M, Toyoda H, Hiraga SI, Yamashita T, Katsuyama Y. Synaptic and genetic bases of impaired motor learning associated with modified experience-dependent cortical plasticity in heterozygous reeler mutants. Cerebral Cortex. 32(3): 504-519, 2022. doi: 10.1093/cercor/bhab227.

2021

Original papers

  • Takaoka R, Kuyama K, Yatani H, Ishigaki S, Kayashima H, Koishi Y, Kato T, Egusa H, Uchiyama Y, Nakatani A, Shimamoto H. Involvement of an FTO gene polymorphism in the temporomandibular joint osteoarthritis. Clinical Oral Investigation,26(3): 2965-2973, 2021 [Open access]
  • Yano H, Matsuura Y, Katagiri A, Higashiyama M, Toyoda H, Sato H, Ueno Y, Uzawa N, Yoshida A, Kato T. Changes in cortical, cardiac, and respiratory activities in relation to spontaneous rhythmic jaw movements in ketamine-anesthetized guinea pigs. Eur J Oral Sci. 129(6): e12817, 2021. doi: 10.1111/eos.12817.
  • Shiraishi Y, Tachibana M, Shirota A, Mohri I, Taniike M, Yamashiro T, Kato T. Relationships between cortical, cardiac, and arousal-motor activities in the genesis of rhythmic masticatory muscle activity across sleep cycles in primary sleep bruxism children. Sleep. 44(11): zsab156, 2021. doi: 10.1093/sleep/zsab156.
  • Okada S, Iwata K, Katagairi A. Pathognomonic Hypersensitivity of the Oral Mucosa and Tongue Induced by Diabetes Mellitus Accompanied by Saliva Reduction in Rats. J Oral Facial Pain Headache. 35(1): 54-61, 2021. doi: 10.11607/ofph.2790.
  • Hijiya K, Masuda Y, Miyamoto T, Shimono R, Kato T, Kageyama T, Yamada K. Age-related differences in maximum voluntary lip-closing force and ability to control lip-closing force. J Oral Biosci. 63(2): 210-216, 2021. doi: 10.1016/j.job.2021.02.002.
  • Imai H, Haraki S, Tsujisaka A, Okura M, Adachi H, Ohno Y, Yatani H, Kato T. A lack of specific motor patterns between rhythmic/non-rhythmic masticatory muscle activity and bodily movements in sleep bruxism. J Prosthodont Res. 65(3): 415-420, 2021. doi: 10.2186/jpr.JPR_D_20_00012.
  • Shirota A, Kamimura M, Kishi A, Adachi H, Taniike M, Kato T. Discrepancies in the time course of sleep stage dynamics, electroencephalographic activity and heart rate variability over sleep cycles in the adaptation night in healthy young adults. Frontiers in Physiology. 12: 623401, 2021. doi: 10.3389/fphys.2021.623401.
  • Toyoda H, Katagiri A, Kato T, Sato H. Intranasal Administration of Rotenone Reduces GABAergic Inhibition in the Mouse Insular Cortex Leading to Impairment of LTD and Conditioned Taste Aversion Memory. International Journal of Molecular Sciences. 22(1): 259. doi: 10.3390/ijms22010259.

Reviews

  • Lavigne G, Kato T, Herrero Babiloni A, Huynh N, Dal Fabbro C, Svensson P, Aarab G, Ahlberg J, Baba K, Carra MC, Cunha TCA, Gonçalves DAG, Manfredini D, Stuginski-Barbosa J, Wieckiewicz M, Lobbezoo F. Research routes on improved sleep bruxism metrics: Toward a standardised approach. J Sleep Res. 30(5): e13320, 2021. doi: 10.1111/jsr.13320.

2020

Original papers

  • Yoshizaki A, Mohri I, Yamamoto T, Shirota A, Okada S, Murata E, Hoshino K, Kato-Nishimura K, Matsuzawa S, Kato T, Taniike M. An Interactive Smartphone App, Nenne Navi, for Improving Children’s Sleep: Pilot Usability Study. JMIR Pediatrics and Parenting 3(2) e22102 - e22102 2020年12月1日
  • Haraki S, Tsujisaka A, Toyoda R, Shiraishi Y, Adachi H, Ishigaki S, Yatani H, Taniike M, Kato T. First night effect on polysomnographic sleep bruxism diagnosis varies among young subjects with different degrees of rhythmic masticatory muscle activity.　Sleep Medicine. doi: 10.1016/j.sleep.2020.08.012
  • Okura M, Nonoue S, Tsujisaka A, Haraki S, Yokoe C, Taniike M, Kato T. Polysomnographic analysis of respiratory events during sleep in young non-obese Japanese adults without clinical complaints of sleep apnea. J Clin Sleep Med. 2020;16(8):1303-1310. doi: 10.5664/jcsm.8498. Online ahead of print.
  • Toyoda H, Kawano T, Sato H, Kato T. Cellular mechanisms underlying the rapid depolarization caused by oxygen and glucose deprivation in layer III pyramidal cells of the somatosensory cortex. Neuroscience Research （doi: 10.1016/j.neures.2020.03.003）ahead of print，2020.
  • Kishi A., Haraki S., Toyota R., Shiraishi Y., Kamimura M., Taniike M., Yatani H., Kato T.　Sleep stage dynamics in young patients with sleep bruxism. Sleep, 43(1):zsz202, doi: 10.1093/sleep/zsz202, 2020.
  • Suzuki Y., Rompre P., Mayer P., Kato T., Okura K., Lavigne GJ. Changes in oxygen and carbon dioxide in the genesis of sleep bruxism: a mechanism study. Journal of Prosthodontic Research, 64(1):43-47, 2020.
  • Kang Y., Saito M., Toyoda H. Molecular and regulatory mechanisms of desensitization and resensitization of GABAa receptors with a special reference to propofol/barbiturate. International Journal of Molecular Sciences 21(2),563, 2020.

Reviews

  • Lobbezoo F, Lavigne GJ, Kato T, Almeida FR, Aarab G. The face of Dental Sleep Medicine in the 21st century. Journal of Oral Rehabilitation 47(12) 1579 - 1589 2020年12月
  • Katagiri A*, Kato T. Multi-dimensional role of the parabrachial nucleus in regulating pain-related affective disturbances in trigeminal neuropathic pain. Journal of Oral Science, 62(2): 160-164, 2020.
  • 福井健一，加藤隆史，機械学習による睡眠評価と睡眠改善に向けて，特集 人工知能技術の医療応用，人工知能，35(4):495-503, 2020.　

2019

Original papers

  • Miyamoto T., Yamada K., Hijiya K., Kageyama T., Kato T., Sugo H., Shimono R., Masuda Y. Ability to control directional lip-closing force during voluntary lip pursing in healthy young adults. Journal of Oral Rehabilitation, 46: 526-532, 2019.
  • Nochino T., Ohno Y., Kato T., Taniike M., Okada S. Sleep stage estimation method using a camera for home use. Biomedical Engineering Letters 9:257–265, 2019.
  • Yamada K., Higashiyama M., Toyoda H., Masuda Y., Kogo M., Yoshida A., Kato T.　Experimentally-induced rhythmic jaw muscle activities during non-rapid eye movement sleep in freely moving guinea pigs. Journal of Sleep Research, 28(5): e12823, 2019.
  • Haraki S., Tsujisaka A., Nonoue S., Nochino T., Kamimura M., Adachi H., Ishigaki S., Yatani H., Taniike M., Kato T. Sleep quality, psychological profiles, cardiac activity and salivary biomarkers in young subjects with different degrees of rhythmic masticatory muscle activity: a polysomnography study. Journal of Oral & Facial pain and Headache, 33:150-113, 2019.
  • Toyoda H. Nicotinic activity layer specifically modulates synaptic potentiation in the mouse insular cortex. European Journal of Neuroscience50(3): 2211-2223 , 2019.
  • Toyoda H. Interaction of nicotinic acetylcholine receptors with dopamine receptors in synaptic plasticity of the mouse insular cortex. Synapse, 73(7):,e22094, 2019.
  • Toyoda H. Role of nicotinic acetylcholine receptors for modulation of microcircuits in the agranular insular cortex. Journal of Oral Biosciences, 61(1): 5-11, 2019.
  • Okada S., Katagiri A., Saito H., Lee J., Ohara K., Iinuma T., Bereiter D.A., Iwata K. Differential activation of ascending noxious pathways associated with trigeminal nerve injury. Pain, 160(6): 1342-1360, 2019.
  • Okada S., Katagiri A., Saito H., Lee J., Ohara K., Iinuma T., Iwata K. Functional involvement of nucleus tractus solitarii neurons projecting to the parabrachial nucleus in trigeminal neuropathic pain. Journal of Oral Science, 61(2): 370-378, 2019.
  • Okada S., Saito H., Matsuura Y., Mikuzuki L., Sugawara S., Onose H., Asaka J., Ohara K., Lee J., Iinuma T., Katagiri A., Iwata K. Upregulation of calcitonin gene-related peptide, neuronal nitric oxide synthase, and phosphorylated extracellular signal-regulated kinase 1/2 in the trigeminal ganglion after bright light stimulation of the eye in rats. Journal of Oral Science, 61(1): 146-155, 2019.

2018

Original papers

  • Matoba H., Kanayama H., Kato T., Hossain MZ., Kitagawa J., Takehana Y., Yamada K., Masuda Y. Temporal change in the occlusal vertical dimension and its involvement in modulation of jaw movement in bite-reduced animals. Journal of Oral Science, 60:170-176, 2018.
  • Tsujisaka A., Haraki S., Nonoue S., Mikami A., Adachi H., Mizumori T., Yatani H., Yoshida A., Kato T. The occurrence of respiratory events in young subjects with a frequent rhythmic masticatory muscle activity: a pilot study. Journal of Prosthodontic Research. 62(3):317-323, 2018.
  • Kato T., Toyota R., Haraki S., Yano H., Higashiyama M., Ueno Y., Yano H., Sato F., Yatani H., Yoshida A. Comparison of rhythmic masticatory muscle activity during non-rapid eye movement sleep in guinea pigs and humans. J Sleep Res, 27(4):e12608. doi: 10.1111/jsr.12608, 2018.
  • Kawasaki Y., Saito M., Won J., Bae J.Y., Sato H., Toyoda H., Kuramoto E., Kogo M., Tanaka T., Kaneko T., Oh S.B., Bae Y.C., Kang Y. Inhibition of GluR current in microvilli of sensory neurons via Na+ -microdomain coupling among GluR, HCN channel and Na+/K+ pump. Frontiers in Cellular Neuroscience, 12,113, 2018.
  • Toyoda H. Nicotine facilitates synaptic depression in layer V pyramidal neurons of the mouse insular cortex. Neuroscience Letters, 672: 78-83 , 2018.
  • Nishimura K., Ohta M., Saito M., Morita-Isogai Y., Sato H., Kuramoto E., Yin D.X., Maeda Y., Kaneko T., Yamashiro T., Takada K., Oh S.B., Toyoda H., Kang Y. Electrophysiological and morphological properties of α and γ motoneurons in the rat trigeminal motor nucleus. Frontiers in Cellular Neuroscience, 12,9, 2018.
  • Watase T., Shimizu K., Ohara K., Komiya H., Kanno K., Hatori K., Noma N., Honda K., Tsuboi Y., Katagiri A., Shinoda M., Ogiso B., Iwata K. Role of medullary astroglial glutamine synthesis in tooth pulp hypersensitivity associated with frequent masseter muscle contraction. Molecular Pain, 14, 2018.

Reviews

  • Lobbezoo F., Ahlberg J., Raphael K.G., Wetselaar P., Glaros A.G., Kato T., Santiago V., Winocur E., De Laat A., De Leeuw R., Koyano K., Lavigne G.J., Svensson P., Manfredini D. International consensus on the assessment of bruxism: Report of a work in progress. J Oral Rehabil,45:837-844, 2018. doi: 10.1111/joor.12663, 2018.

2017

Original papers

  • Sato F., Uemura Y., Kanno C., Tsusumi Y., Tomita A., Oka A., Kato T., Uchino K., Murakami J., Haque T., Tachibana Y., Yoshida A. Thalamo-insular pathway conveying orofacial muscle proprioception in the rat, Neuroscience, 365:158-178, 2017.
  • Wu H., Kato T., Numao M., Fukui KI. Statistical sleep pattern modelling for sleep quality assessment based on sound events. Health Inf Sci Syst, 5(1):11, 2017. doi: 10.1007/s13755-017-0031-z, 2017.
  • Wu H., Kato T., Yamada T., Numao M., Fukui K. Personal Sleep Pattern Visualization using Sequence-based Kernel Self-Organizing Map on Sound Data. Artificial Intelligence in Medicine, 80:1-10, 2017.
  • Sato H., Kawano T., Yin D.X., Kato T., Toyoda H. Niconitic activity depresses synaptic potentiation in mouse insular cortex. Neuroscience, 358:13-27, 2017.
  • Nonoue S., Mashita M., Haraki S., Mikami A., Adachi H., Yatani H., Yoshida A., Taniike M., Kato T*. Inter-scorer reliability of sleep assessment using EEG and EOG recording system in comparison to polysomnography. Sleep Biol Rhythm, 15:39-48, 2017.
  • Sakai T., Kato T., Yoshizawa S., Suganuma T., Takaba M., Ono Y., Yoshida Y., Yoshizawa A., Kurihara T., Ishii M., Kawana F., Kiuchi Y., Baba K. Effect of clonazepam and clonidine on primary sleep bruxism: a double-blind, crossover, placebo-controlled trial. Journal of Sleep Research, 26:73-83, 2017.
  • Lee WK., Bae JH., Hu SK., Kato T., Kim ST. Anatomical recommendations for safe botulinum toxin injection areas in temporalis muscle. Surgical and Radiologic Anatomy, 39:263-269, 2017.
  • Muraki H., Okura M.*, Kato T., Taniguchi M., Ohi M. A stereotyped sequence from EEG arousals to nocturnal groaning events with or without the intervening sleep bruxism in catathrenia. Sleep Medicine, 2:1-3, 2017.
  • Sato H., Kawano T., Yin D.X., Kato T., Toyoda H. Nicotinic activity depresses synaptic potentiation in layer V pyramidal neurons of mouse insular cortex. Neuroscience, 358: 13-27, 2017.
  • Morita-Isogai Y., Sato H., Saito M., Kuramoto E., Yin D.X., Kaneko T., Yamashiro T., Takada K., Oh S.B., Toyoda H., Kang, Y. A distinct functional distribution of α and γ motoneurons in the rat trigeminal motor nucleus. Brain Structure and Function, 222(7): 3231-3239, 2017.
  • Sugawara S., Okada S., Katagiri A., Saito H., Suzuki T., Komiya H., Kanno K., Ohara K., Iinuma T., Toyofuku A., Iwata K. Interaction between calcitonin gene-related peptide-immunoreactive neurons and satellite cells via P2Y12R in the trigeminal ganglion is involved in neuropathic tongue pain in rats. European Journal of Oral Sciences, 125(6):444-452, 2017
  • Mikuzuki L., Saito H., Katagiri A., Okada S., Sugawara S., Kubo A., Ohara K., Lee J., Toyofuku A., Iwata K. Phenotypic change in trigeminal ganglion neurons associated with satellite cell activation via extracellular signal-regulated kinase phosphorylation is involved in lingual neuropathic pain. European Journal of Neuroscience, 46(6): 2190-2202 , 2017.
  • Saito H., Katagiri A., Okada S., Mikuzuki L., Kubo A., Suzuki T., Ohara K., Lee J., Gionhaku N., Iinuma T., Bereiter D.A., Iwata, K. Ascending projections of nociceptive neurons from trigeminal subnucleus caudalis: A population approach. Experimental Neurology, 293: 124-136, 2017.
  • Kubo A., Shinoda M., Katagiri A., Takeda M., Suzuki T., Asaka J., Yeomans D.C., Iwata, K. Oxytocin alleviates orofacial mechanical hypersensitivity associated with infraorbital nerve injury through vasopressin-1A receptors of the rat trigeminal ganglia. Pain, 158(4): 649-659, 2017.

Reviews

  • Iwata, K., Katagiri A., Shinoda M. Neuron-glia interaction is a key mechanism underlying persistent orofacial pain. Journal of Oral Science, 59(2): 173-175, 2017.

2016

Original papers

  • H. Wu, Kato T, Yamada T, Numao M, Fukui K*. Sleep Pattern Discovery via Visualizing Cluster Dynamics of Sound Data. Trends in Applied Knowledge-Based Systems and Data Science (LNAI 9799):460-471, 2016.
  • Ikawa Y, Mochizuki A, Katayama K, Kato T, Ikeda M, Abe Y, Nakamura S, Nakayama K, Wakabayashi N, Baba K, Inoue T*. Citalopram modulates jaw-closing muscle activity during non-REM sleep in mice. Neuroscience Research, 113:48-55, 2016.
  • Tachibana M, Kato T*, Kato-Nishimura K, Matsuzawa S, Mohri I, Taniike M. Associations of sleep bruxism with age, sleep apnea and daytime problematic behaviors in children. Oral Diseases, 22:557-565, 2016.
  • Kato T*, Abe K, Mikami A, Sugita H, Muraki H, Okura M, Ohi M, Taniguchi M. Subjective oropharyngeal symptoms for abnormal swallowing in Japanese patients with obstructive sleep apnea syndrome: a descriptive questionnaire study. Journal of Craniomandibular and Sleep Practice, 34(2):95-99, 2016.
  • Fujio T, Sato F, Tachibana Y, Kato T, Tomita A, Higashiyama K, Ono T, Maeda Y, Yoshida A*. Revisiting the supratrigeminal nucleus in the rat. Neuroscience, 324:307-320, 2016.
  • Ohara H, Tachibana Y, Fujio T, Takeda-Ikeda R, Sato F, Oka A, Kato T, Ikenoue E, Yamashiro T, Yoshida A*. Direct projection from the lateral habenula to the trigeminal mesencephalic nucleus in rats. Brain Research, 1630:183-97, 2016.
  • Kaede K, Kato T, Yamaguchi M, Nakamura N, Yamada K, Masuda Y*. Effects of lip-closing training on maximum voluntary lip-closing force during lip pursing in healthy young adults. Journal of Oral Rehabilitation, 43(3):169-75, 2016.
  • Tamaki K, Ishigaki S, Ogawa T, Oguchi H, Kato T, Suganuma T, Shimada A, Sadamori S, Tsukiyama Y, Nishikawa Y, Masumi S, Yamaguchi T, Aita H, Ono T, Kondo H, Tsukasaki H, Fueki K, Fujisawa M, Matsuka Y, Baba K, Koyano K. Japan Prosthodontic Society position paper on “occlusal discomfort syndrome”. J Prosthodontic Research, 60: 156-166, 2016.
  • Kang Y., Sato H., Saito M., Yin D.X., Park S.K., Oh S.B., Bae Y.C., Toyoda,H. A role of CB1R in inducing-rhythm coordination between the gustatory and gastrointestinal insula. Scientific Reports, 6,32529, 2016.
  • Kawakami S., Sato H., Sasaki A.T., Tanabe H.C., Yoshida Y., Saito M., Toyoda H., Sadato N., Kang, Y. The brain mechanisms underlying the perception of pungent taste of capsaicin and the subsequent autonomic responses. Frontiers in Human Neuroscience, 9,720, 2016.
  • Okamoto K., Emura N., Sato H., Fukatsu Y., Saito M., Tanaka C., Morita Y., Nishimura K., Kuramoto E., Yin D.X., Furutani K., Okazawa M., Kurachi Y., Kaneko T., Maeda Y., Yamashiro T., Takada K., Toyoda H., Kang Y. The possible role of TASK channels in rank-ordered recruitment of motoneurons in the dorsolateral part of the trigeminal motor nucleus. eNeuro, 3(3): 497-506, 2016.