Li H, Yamaguchi S, Lee C, Benalcazar-Jalkh EB, Bonfante EA, Imazato S, In silico nonlinear dynamic finite-element analysis for biaxial flexural strength testing of CAD/CAM materials. J Prosthodont Res (in press).

Kinoshita M, Yamada S, Sasaki J, Suzuki S, Kajikawa T, Iwayama T, Fujihara C, Imazato S, Murakami S. Mice Lacking PLAP-1/Asporin Show Alteration of Periodontal Ligament Structures and Acceleration of Bone Loss in Periodontitis. Int J Mol Sci 24(21):15989, 2023.

Jiravejchakul N, Abe GL, Loza M, Park S, Matangkasombut P, Sasaki JI, Imazato S. Intercellular crosstalk in adult dental pulp is mediated by heparin-binding growth factors Pleiotrophin and Midkine. BMC Genomics 24(1): 184, 2023.

Hirata R, Sampaio CS, Atria PJ, Giannini M, Coelho PG ,Yamaguchi S. Effect of high-radiant emmitance and short curing time on polymerization shrinkage vectors of bulk fill composites. Oper Dent 48(1): 51-58, 2023.

Hoshino IAE, dos Santos PH, Briso LF, Sundfeld RH, Yamaguchi S, Rocha EP, Anchieta RB. Biomechanical performance of three fiberglass post cementation techniques: imaging, in vitro, and in silico analysis. J Prosthodont Res 67(1): 103-111, 2023.

Lee C, Yamaguchi S, Imazato S. Quantitative evaluation of the degradation amount of the silane coupling layer of computer-aided design/computer-aided manufacturing resin composites by water absorption. J Prosthodont Res 67(1): 55-61, 2023.

Xiao L, Shiwaku Y, Hamai R, Baba K, Tsuchiya K, Imazato S, Sasaki K, Suzuki O. Osteogenic capacity of octacalcium phosphate involving macrophage polarization. J Biomed Mater Res A (in press).

Min S, Wang YC, Hamaguchi J, Chang CC, Kim T, Carames G, Gil A, Yamaguchi S, Imazato S, Angelov N. Kinetics of phenotype modificatin therapy with VISTA: a retrospective case series using 3D digital analysis. Int J Periodontics Restorative Dent (in press).

Salim I, Seseogullari-Dirihan R, Imazato S, Tezvergil-Mutluay A. The inhibitory effects of various ions released from S-PRG fillers on dentin protease activity. Dent Mater J (in press).

Li A, Sasaki JI, Inubushi T, Abe GL, Nor JE, Yamashiro T, Imazato S. Role of heparan sulfate in vasculogenesis of dental pulp stem cells. J Dent Res 102(2): 207-216, 2023.

Kudo H, Wakabayashi K, Sasaki JI, Tamiya S, Ishigaki S. Fracture strength and behavior of resin-faced CAD/CAM anterior crowns. Dent Mater J 42(1): 86-91, 2023.

Sakai T, Li H, Shimada T, Kita S, Iida M, Lee C, Nakano T, Yamaguchi S, Imazato S. Development of artificial intelligence model for supporting implant drilling protocol decision making. J Prosthodont Res (in press).

Karaer O, Yamaguchi S, Imazato S, Terzioglu H. In silico finite element analysis of implant-supported CAD/CAM resin composite crowns. J Prosthodont 32(3): 259-266, 2023.

Kitagawa H, Kohno T, Deng F, Abe GL, Sakai H, Fan YS, Wu T, Sasaki JI, Imazato S*. Metal-doped silicate and phosphate glasses for antibacterial dental biomaterials. Biomater Investig Dent (in press).

Imazato S, Nakatsuka T, Kitagawa H, Sasaki JI, Yamaguchi S, Ito S, Takeuchi H, Nomura R, Nakano K. Multiple-ion releasing bioactive surface pre-reacted glass-ionomer (S-PRG) filler: innovative technology for dental treatment and care. J Funct Biomater 14(4): 236, 2023.

Yamaguchi S, Li H, Imazato S. Materials informatics for developing new restorative dental materials: A narrative review. Front Dent Med 4: 1123976, 2023.

北川 晴朗, 今里 聡.バイオセラミックス系根管充填シーラーの現状と有用性. 日本歯科医師会雑誌 75(11): 841-849, 2023.


Deng F, Sakai H, Kitagawa H, Kohno T, Thongthai P, Liu Y, Kitagawa R, Abe GL, Sasaki JI, Imazato S. Fabrication of pH-responsive Zn2+-releasing glass particles for smart antibacterial restoratives. Molecules 27, 7202, 2022.

Delgado A, Sauro S, Loguercio AD, Della Bona A, Mazzoni A, Collares FM, Staxrud F, Ferracane JL, Tsoi JKH, Amato J, Neuhaus KW, Ceballos L, Breschi L, Hanning M, Melo MAS, Ozcan M, Scotti N, Opdam NJM, Yamaguchi S, Paris S, Trukun LS, Domejean S, Rosa V, Palin WM, Schwendicke F. RoBDEMAT: A risk of bias tool and guideline to support reporting of pre-clinical dental materials research and assessment of systematic reviews. J Dent 127: 104350, 2022.

Kondo S, Hazama H, Tomioka Y, Mine A, Yamaguchi S, Okumura S, Tanimoto H, Yasuo K, Yoshikawa K, Yamamoto K, Awazu K. Demonstration of an optical dentin hardness measureing device using bovine dentin with different demineralization times. J Biomed Opt 27(10): 105004, 2022.

Benalcazar Jalkh EB, Bergamo ETP, Campos TMB, de Araujo-Junior ENS, Lopes ACO, Tebcherani SM, Yamaguchi S, Genova LA, Gierthmuehlen PC, Witek L, Coelho PG, Bonfante EA. Stability of fatigued and aged ZTA compared to 3Y-TZP and Al2O3 ceramic systems. J Mech Behav Biomed Mater 135: 105451, 2022.

L Abe G, Tsuboi R, Kitagawa H, Sasaki JI, Li A, Kohno T, Imazato S. Poly(lactic acid/caprolactone) bilayer membrane blocks bacterial penetration. J Periodontal Res 57(3): 510-518, 2022.

Mehdawi IM, Kitagawa R, Kitagawa H, Yamaguchi S, Hirose N, Kohno T, Imazato S. Incorporation of chlorhexidine in self-adhesive resin cements. Dent Mater J 41(5): 675-681, 2022.

Li H, Sakai T, Tanaka A, Ogura M, Lee C, Yamaguchi S, Imazato S. Interpretable AI expores effective components of CAD/CAM resin composites. J Dent Res 101(11): 1363-1371, 2022.

Thongthai P, Kitagawa H, Noree S, Iwasaki Y, Liu YH, Abe GL, Yamaguchi S, Imazato S. Evaluation of the long-term antibiofilm effect of a surface coating with dual functionality of antibacterial and protein-repellent effects. Dent Mater J 41(2): 189-196, 2022.

Nakase Y, Yamaguchi S, Okawa R, Nakano K, Kitagawa H, Imazato S. Physical properties and wear behavior of CAD/CAM resin composite blocks containing S-PRG filler for restoring primary molar teeth. Dent Mater 38(1): 158-168, 2022.

Chen Y, Zhai Z, Li H, Yamada S, Matsuoka T, Ono S, Nakano T. Influence of liquid on the tooth surface on the accuracy of intraoral scanners: an in vitro study. J Prosthodont 31(1): 59-64, 2022.

山口 哲,堺 貴彦,李 ??,今里 聡.補綴治療/診断を支援するAIの構築を目指して.日本歯科理工学会誌 41(2):107-110, 2022.


Kohno T, Kitagawa H, Tsuboi R, Nishimura Y, Imazato S. Establishment of novel in vitro culture system with the ability to reproduce oral biofilm formation on dental materials. Sci Rep 11(1): 21188, 2021.

Suzaki N, Yamaguchi S, Nambu E, Tanaka R, Imazato S, Hayashi M. Fabricated CAD/CAM post-core using glass fiber-reinforced resin shows innovative potential in restoring pulpless teeth. Materials 14(20):6199, 2021.

Sasaki JI, Abe GL, Li A, Matsumoto T, Imazato S. Large three-dimensional cell constructs for tissue engineering. Sci Technol Adv Mater 22(1): 571-582, 2021.

Liu YH, Kohno T, Tsuboi R, Thongthai P, Fan D, Sakai H, Kitagawa H, Imazato S. Antibacterial effects and physical properties of a glass ionomer cement containing BioUnion filler with acidity-induced ability to release zinc ion. Dent Mater J 40(6): 1418-1427, 2021.

Thongthai P, Kitagawa H, Iwasaki Y, Noree S, Kitagawa R, Imazato S. Immobilizing bactericides on dental resin via electron-beam irradiation. J Dent Res 100(10):1055-1062, 2021.

Katata C, Sasaki JI, Li A, Abe GL, Nör JE, Hayashi M, Imazato S. Fabrication of vascularized DPSC constructs for efficient pulp regeneration. J Dent Res 100(12):1351-1358, 2021. 

Kitagawa H, Kitagawa R, Tsuboi R, Hirose N, Thongthai P, Sakai H, Ueda M, Ono S, Sasaki JI, Ooya T, Imazato S. Development of endodontic sealers containing antimicrobial-loaded polymer particles with long-term antibacterial effects. Dent Mater 37(8): 1248-1259, 2021.

Sasaki JI, Abe GL, Li A, Thongthai P, Tsuboi R, Kohno T, Imazato S. Barrier membranes for tissue regeneration in dentistry. Biomater Investig Dent 8(1): 54-63, 2021.

Matsuoka T, Nakano T, Yamaguchi S, Ono S, Watanabe S, Sato T, Yatani H. Effects of Implant?Abutment Connection Type and Inter-Implant Distance on Inter-Implant Bone Stress and Microgap: Three-Dimensional Finite Element Analysis. Materials 14(9): 2421, 2021.

El-Askary FS, Yamaguchi S, Mine A, Kitagawa R, Hirose N, Hayashi M. The torsion test offers a new approach for evaluating CAD/CAM material bonding. J Adhes Sci Technol 36(4): 392-409, 2021.

Kohno T, Liu Y, Tsuboi R, Kitagawa H, Imazato S. Evaluation of ion release and the recharge ability of glass-ionomer cement containing BioUnion filler using an in vitro saliva-drop setting assembly. Dent Mater 37(5): 882-893, 2021.

Cobanoglu N, Alptekin T, Kitagawa H, Blatz MB, Imazato S, Ozer F. Evaluation of human pulp tissue response following direct pulp capping with a self-etching adhesive containing MDPB. Dent Mater J 40(3): 689-696, 2021.

Kawashima M, Yamaguchi S,  Mine A, Li H, Imazato S. Novel testing method to evaluate the mechanical strength of self-adhesive resin cements with reflection of cement thickness. Dent Mater J 40(5): 1235-1242, 2021.

Yamaguchi S, Karaer O, Lee C, Sakai T, Imazato S. Color matching ability of resin composites incorporating supra-nano spherical filler producing structural color. Dent Mater 37(5): e269-e275, 2021.

Bergamo ETP, Yamaguchi S, Coelho PG, Lopes ACO, Lee C, Bonfante G, Benalcázar Jalkh EB, de Araújo-Júnior ENS, Bonfane EA. Survival of implant-supported resin-matrix ceramic crowns: in silico and fatigue analyses. Dent Mater 37(3): 523-533, 2021.

Kawashima M, Mine A, Yamaguchi S, Imazato S. Development of novel measurement method for consistency of resin cements. Dent Mater J 40(4): 1063-1067, 2021.

Sakai T, Li H, Abe T, Yamaguchi S, Imazato S. Multi-scale analysis of the influence of filler shapes on the mechanical performance of resin composites using high resolution nano-CT images. Dent Mater 37(1): 168-174, 2021.

Morita M, Kitagawa H, Nakayama K, Kitagawa R, Yamaguchi S, Imazato S. Antibacterial activities and mineral induction abilities of proprietary MTA cements. Dent Mater J 40(2): 297-303, 2021.

Imazato S, Kitagawa H. Oral Biofilms and Modern Dental Materials. Advances Toward Bioactivity. Dental resin-based materials with antibacterial properties: contact inhibition and controlled release. (Ionescu AC, Hahnel S, ed.), Springer, Switzerland, pp. 127-140, 2021.



Zhou W, Zhou X, Huang X, Zhu C, Weir MD, Melo MAS, Bonavente A, Lynch CD, Imazato S, Oates TW, Cheng L, Xu HHK. Antibacterial and remineralizaing nanocomposite inhibit root caries biofilms and protect root dentin hardness at the margins. J Dent: 103344, 2020.

Hayashi M, Momoi Y, Fujitani M, Fukushima M, Imazato S, Kitasako Y, Kubo S, Nakashima S, Nikaido T, Shimizu A, Sugai K, Takahashi R, Unemori M, Yamaki C. Evidence-based consensus for treating incipient enamel caries in adults by non-invasive methods: recommendations by GRADE guideline. Jpn Dent Sci Rev 56(1): 155-163, 2020.

Tsuboi R, Kitagawa H, Imazato S. FGF-2 release and bonding/physical properties of 4-META/MMA-based adhesive resins incorporating small FGF-2-loaded polymer particles. Dent Mater 36(12):1586-1594, 2020.

Inoue S, Yamaguchi S, Uyama H, Yamashiro T, Imazato S. Orthodontic aligner incorporating Eucommia ulmoides exerts low continuous force: in vitro study. Materials 13(18): 4085, 2020.

Yamaguchi S, Katsumoto Y, Hayashi K, Aoki M, Kunikata M, Nakase Y, Lee C, Imazato S. Ftacture origin and crack propagation of CAD/CAM composite crowns by combination of in vitro and in silico approaches. J Mech Behav Biomed Mater 112: 104083, 2020.

Hashimoto M, Kitagawa H, Takahashi Y, Hayashi M, Imazato S. Cytotoxicity of S-PRG fillers: direct exposure of fillers and eluate from the fillers to RAW264 cells. Nano Biomedicine 12(1): 3-10, 2020.

Zhow W, Peng X, Zhou X, Bonavente A, Weir MD, Melo MAS, Imazato S, Oates TW, Cheng L, Xu HHK. Novel nanocomposite inhibiting caries at the enamel restoratino margings in an in vitro saliva-derived biofilm secondary caries model. Int J Mol Sci 21(17): E6369, 2020.

Zhou W, Peng X, Zhou X, Weir MD, Melo MAS, Tay FR, Imazato S, Oates TW, Cheng L, Xu HHK. In vitro evaluation of composite containing DMAHDM and calcium phosphate nanoparticles on recurrent caries inhibition at bovine enamel-restoration margins. Dent Mater 36(10): 1343-1355, 2020.

Thongthai P, Kitagawa H, Kitagawa R, Hirose N, Noree S, Iwasaki Y, Imazato S. Development of novel surface coating composed of MDPB and MPC with dual functionality of antibacterial activity and protein repellency. J Biomed Mater Res B Appl Biomater 108(8): 3241-3249, 2020.

Suzaki N, Yamaguchi S, Hirose N, Tanaka R, Imazato S, Hayashi M. Evaluation of physical properties of fiber-reinforced composite resin. Dent Mater 36(8): 987-996, 2020.
Chen H, Tang Y, Weir MD, Gao J, Imazato S, Oates TW, Lei L, Wang S, Hu T, Xu HHK. Effects of S. mutans gene-modification and antibacterial monomer dimethylaminohexadecyl methacrylate on biofilm growth and acid production. Dent Mater 36(2): 296-309, 2020.

Gao Y, Liang K, Weir MD, Gao J, Imazato S, Tay FR, Lynch CD, Oates TW, Li J, Xu HHK. Enamel remineralization via poly(amido amine) and adhesive resin containing calcium phosphate nanoparticles. J Dent 92: 103262, 2020.

Nihei T, Ohashi K, Hattori M, Imazato S. A surveillance study of the demand of titanium and titanium alloys in Japan. Dent Mater J 39(1): 9-11, 2020.

Han A, Ding H, Tsoi JKH, Imazato S, Matinlinna JP, Chen Z. Prolonged UV-C irradiation is a double-edeged sword on the Zirconia surface. ACS Omega 5(10): 5126-5133, 2020.

Sasaki JI, Yoshimoto I, Katata C, Tsuboi R, Imazato S. Freeze-dry processing of three-dimensional cell constructs for bone graft materials. J Biomed Mater Res B Appl Biomater 108(3): 958-964, 2020.

Abe GL, Sasaki JI, Katata C, Kohno T, Tsuboi R, Kitagawa H, Imazato S. Fabrication of novel poly(lactic acid/caprolactone) bilayer membrane for GBR application. Dent Mater 36(5): 626-634, 2020.

Karaer O, Yamaguchi S, Nakase Y, Lee C, Imazato S. In silico non-linear dynamic analysis reflecting in vitro physical properties of CAD/CAM resin composite blocks. J Mech Behav Biomed Mater 104: 103697, 2020.

Yamaguchi S, Lee C, Karaer O, Ban S, Mine A, Imazato S. Response to the Letter to the Editor: "Predicting the Debonding of CAD/CAM Composite Resin Crowns with AI". J Dent Res 99(2): 234, 2020.

Stocchero M, Jinno Y, Toia M, Jimbo R, Lee C, Yamaguchi S, Imazato S, Becktor J. In silico multi-scale analysis of remodeling peri-implant cortical bone: a comparison of two types of bone structures following an undersized and non-undersized technique. J Mech Behav Biomed Mater 103: 103598, 2020.

Sasaki JI, Zhang Z, Oh M, Pobocik AM, Imazato S, Shi S, Nör JE. VE-cadherin and anastomosis of blood vessels formed by dental stem cells. J Dent Res 99(4): 437-445, 2020.

Lee C, Kashima K, Ichikawa A, Yamaguchi S, Imazato S. Influence of hydrolysis degradation of silane coupling agents on mechanical performance of CAD/CAM resin composites: in silico multi-scale analysis. Dent Mater J 39(5): 803-807, 2020.

Liu Y, Kohno T, Tsuboi R, Kitagawa H, Imazato S. Acidity-induced release of zinc ion from BioUnionTM filler and its inhibitory effects against Streptococcus mutans. Dent Mater J 39(4): 547-553, 2020.

Inoue S, Yamaguchi S, Uyama H, Yamashiro T, Imazato S. Influence of constant strain on the elasticity of thermoplastic orthodontic materials. Dent Mater J 39(3): 415-421, 2020. 

Sasaki JI, Imazato S. Autoclave sterilization of dental handpieces: A literature review. J Prosthodont Res 64(3): 239-242, 2020.

Imazato S, Kohno T, Tsuboi R, Thongtai P, Xu HH, Kitagawa H. Cutting-edge filler technologies to release bio-active components for restorative and preventive dentistry. Dent Mater J 39: 69-79, 2020.

今里 聡,北川晴朗.S-PRGの効果的な活用法―その作用とは?どんな効果があるのか?日本歯科評論 80(2):103-109, 2020.


Li X, Qi M, Dong B, Wang J, Weir MD, Imazato S, Du L, Lynch CD, Xu L, Zhou Y, Wang L, Xu HHK. Novel nanoparticles of cerium-doped zeolitic imidazolate frameworks with dual benefits of antibacterial and anti-inflammatory functions against periodontitis. J Mater Chem B 7(44): 6955-6971, 2019.

Noree S, Thongthai P, Kitagawa H, Imazato S. Iwasaki Y. Reduction of acidic erosion and oral bacterial adhesion through the immobilization of zwitterionic polyphosphoesters on mineral substrates. Chemistry Letters 48(12): 1529-1532, 2019.

Okamoto M, Ali M, Komichi S, Watanabe M, Huang H, Ito Y, Miura J, Hirose Y, Mizuhira M, Takahashi Y, Okuzaki D, Kawabata S, Imazato S, Hayashi M. Surface pre-reacted glass filler contributes to teritary dentin formation through a mechanism different than that of hydraulic calcium-silicate cement. J Clin Med 8(9): E1440, 2019.

Kang J, Izutani N, D'angelo M, Buis W, Wang Y, Blatz M, Imazato S. Assaying endogenous matrix metalloproteinases (MMPs) in acid-etched dentinal cavity walls. Dent Mater J 38(6): 934-939, 2019.

Stocchero M, Jinno Y, Toia M, Ahmad M, Papia E, Yamaguchi S, Bector JP. Intraosseous temperature change during installation of dental implants with two different surfaces and different drilling protocols. An in vivo study in sheep. J Clin Med 8(8): E1198, 2019.

Yamaguchi S, Lee C, Karaer O, Ban S, Mine A, Imazato S. Predicting the debonding of CAD/CAM composite resin crowns using AI. J Dent Res 98(11): 1234-1238, 2019.
Sasaki JI, Kiba W, Abe GL, Katata C, Hashimoto M, Kitagawa H, Imazato S. Fabrication of strontium-releasable inorganic cement by incorporation of bioactive glass. Dent Mater 35(5): 780-788, 2019.

Sasaki JI, Katata C, Abe GL, Matsumoto T, Imazato S. Fabricating large-scale three-dimensional constructs with living cells by processing with syringe needles. J Biomed Mater Res A 107(4): 904-909, 2019.

Koytchev E, Yamaguchi S, Shin-no Y, Suzaki N, Okamoto M, Imazato S, Datcheva M, Hayashi M, Comprehensive micro-mechanical characterization of experimental direct core build-up resin composites with different amounts of filler contents. Dent Mater J 38(5): 743-749, 2019.

Lee C, Yamaguchi S, Ohta K, Imazato S. Mechanical properties of computer-aided design/computer-aided manufacturing resin composites assuming perfect silane coupling using in silico homogenization of cryo-electron microscopy images. J Prosthodont Res 63(1): 90-94, 2019. 

Takahashi Y, Okamoto M, Komichi S, Imazato S, Nakatsuka T, Sakamoto S, Kimoto K, Hayashi M. Application of a direct pulp capping cement containing S-PRG filler. Clin Oral Investig 23(4): 1723-1731, 2019.

壷井莉理子,北川晴朗,今里 聡.組織再生誘導能を備えたFGF-2担持ポリマー粒子配合レジンセメントの開発.大阪大学歯学雑誌 64(1): 9-12, 2019.

山口 哲.In vitro実験と数理科学の融合に基づく修復材料の高性能化の試み.大阪大学歯学雑誌 63(2): 7-10, 2019.

今里 聡,北川晴朗. サホライドによる根面う蝕のマネジメント~”古くて新しい”フッ化ジアンミン銀製剤の有用性を再考する~. 日本歯科医師会雑誌 72(5):43-51, 2019.


Yamaguchi S, Kani R, Kawakami K, Tsuji M, Inoue S, Lee C, Kiba W, Imazato S. Fatigue behavior and crack initiation of CAD/CAM resin composite molar crowns. Dent Mater 34(10): 1578-1584, 2018.

Zhang N, Zhang K, Xie X, Dai Z, Zhao Z, Imazato S, Al-Dulaijan YA, Al-Qami FD, Weir MD, Reynolds MA, Bai Y, Wang L, Xu HHK. Nanostrctured polymetric materials with protein-repellent and anti-caries properties for dental applications. Nanomaterials (basel) 8(6): E393, 2018.

Yue S, Wu J, Zhang Q, Zhang K, Weir MD, Imazato S, Bai Y, Hu HHK. Novel dental adhesive resin with crack self-healing, antimicrobial and remineralization properties. J Dent 75:48-57, 2018.

Itoh Y, Sasaki JI, Hashimoto M, Katata C, Hayashi M, Imazato S. Pulp regeneration by 3-dimensional dental pulp stem cell constructs. J Dent Res 97:1137-1143, 2018.

Muratovska I, Kitagawa H, Hirose N, Kitagawa R, Imazato S. Antibacterial activity and dentin bonding ability of combined use of Clearfil SE Protect and sodium hypochiorite. Dent Mater J 37(3): 620-627, 2018.

Tsuboi R, Sasaki JI, Kitagawa H, Yoshimoto I, Takeshige F, Imazato S. Development of a novel dental resin cement incorporating FGF-2-loaded polymer particles with the ability to promote tissue regeneration. Dent Mater 34(4): 641-648, 2018.

Yoshimoto I, Sasaki JI, Tsuboi R, Yamaguchi S, Kitagawa H, Imazato S. Development of layered PLGA membranes for periodontal tissue regeneration. Dent Mater 34(4): 538-550, 2018.

Yamaguchi S, Mehdawi IM, Sakai T, Abe T, Inoue S, Imazato S. In vitro/in silico investigation of failure criteria to predict flexural strength of composite resins. Dent Mater J 37(1): 152-156, 2018.

Yamaguchi S, Yamanishi Y, Machado LS, Matsumoto S, Tovar N, Coelho PG, Thompson VP, Imazato S. In vitro fatigue tests and in silico finite element analysis of dental implants with different fixture/abutment joint types using computer-aided design models. J Prosthodont Res 62(1): 24-30, 2018.


Hashimoto M, Yanagiuchi H, Kitagawa H, Yoshitomo Honda. Inhibitory effect of platinum nanoparticles on biofilm formation of oral bacteria. Nano Biomed 9(2): 77-82, 2017.

Hashimoto M, Yanagiuchi H, Kitagawa H, Yamaguchi S, Honda Y, Imazato S. Effect of metal nanoparticles on biofilm formation of Streptococcus mutans. Nano Biomed 9(2): 61-68, 2017.

Hashimoto M, Hirose N, Kitagawa H, Yamaguchi S, Imazato S. Improving the durability of resin-dentin bonds with an antibacterial monomer MDPB. Dent Mater J 37(4): 620-627, 2017.

Imazato S, Kitagawa H, Tsuboi R, Kitagawa R, Thongthai P, Sasaki JI.. Non-biodegradable polymer particles for drug delivery: A new technology for "bio-active" restorative materials. Dent Mater J 36(5): 524-532, 2017. 
Sampaio CS, Atria PJ, Rueggeberg FA, Yamaguchi S, Giannini M, Coelho PG, Hirata R, Puppin-Rontani RM. Effect of blue and violet light on polymerization shrinkage vectors of a CQ/TPO-containing composite. Dent Mater 33(7): 796-804, 2017.
Miyajima H, Ozer F, Imazato S, Mante FK. Surface characteristics of bioactive Ti fabricated by chemical treatment for cartilaginoue-integration. Mater Sci Eng C 78(1): 495-502, 2017.
Kitagawa H, Takeda K, Tsuboi R, Hayashi M, Sasaki JI, Imazato S. Influence of polymerization properties of 4-META/MMA-based resin on the activity of fibroblast growth factor-2. Dent Mater J 36(6): 724-730, 2017.
Yamaguchi S, Inoue S, Sakai T, Abe T, Kitagawa H, Imazato S. Multi-scale analysis of the effect of nano-filler particles diameter on the physical properties of CAD/CAM composite resin blocks. Comput Methods Biomech Biomed Engin 20(7) :714-719, 2017.
Hashimoto M, Kawakami H, Kawai K, Imazato S. Effect of particle size of gold nanoparticles on matrix metalloprotease inhibition, cytotoxicity and genotoxicity. J Biomater Tissue Eng 7(2): 139-146, 2017.
Yamaguchi S, Anchieta RB, Guastaldi FP, Tovar N, Tawara D, Imazato S, Coelho PG. In silico analysis of the biomechanical stability of commercially pure Ti and Ti-15Mo plates for the treatment of mandibular angle fracture. J Oral Maxillofac Surg 75(5): 1004.e1-1004.e9, 2017.


山口 哲, 今里 聡. 金属に代わる歯科用修復材料の創製を目指して. 生産と技術 69(3):92-95, 2017.


Kamonwanon P, Hirose N, Yamaguchi S, Sasaki JI, Kitagawa H, Kitagawa R, Thaweboon S, Srikhirin T, Imazato S. SiO2-nanocomposite film coating of CAD/CAM composite resin blocks improves surface hardness and reduces susceptibility to bacterial adhesion. Dent Mater J 36(1): 88-94, 2016.
Hirose N, Kitagawa R, Kitagawa H, Maezono H, Mine A, Hayashi M, Haapasalo M, Imazato S. Development of a Cavity Disinfectant Containing Antibacterial Monomer MDPB. J Dent Res 95(13): 1487-1493, 2016.
Moriwaki H, Yamaguchi S, Nakano T, Yamanishi Y Imazato S, Yatani H. Influence of implant length and diameter, bicortical anchorage, and sinus augmentation on bone stress distribution: three-dimensional finite element analysis. Int J Oral Maxillofac Implants 31(4): e84-91, 2016.
Wang L, Xie X, Imazato S, Weir MD, Reynolds MA, Xu HH. A protein-repellent and antibacterial nanocomposite for Class-V restorations to inhibit periodontitis-related pathogens. Mater Sci Eng C Mater Biol Appl 67: 702-710, 2016.
Miyajima H, Ishimoto T, Ma S, Chen J, Nakano T, Imazato S. In vitro assessment of a calcium-fluoroaluminosilicate glass-based desensitizer for the prevention of root surface demineralization. Dent Mater J 35(3): 399-407, 2016.
Okawa H, Kayashima H, Sasaki JI, Miura J, Kamano Y, Kosaka Y, Imazato S, Yatani H, Matsumoto T, Egusa H. Scaffold-free fabrication of osteoinductive cellular constructs using mouse gingiva-derived induced pluripotent stem cells. Stem Cell Int 2016: 6240794, 2016.
Oka Y, Sasaki JI, Wakabayashi K, Nakano Y, Okamura S, Nakamura T, Imazato S, Yatani H. Fabrication of a radiopaque fit-testing material to evaluate the three-dimensional accurac of dental prostheses. Dent Mater 32(7): 921-928, 2016.
Kitagawa H, Izutani N, Kitagawa R, Maezono H, Yamaguchi M, Imazato S. Evolution of resistance to cationic biocides in Streptococcus mutans and Enterococcus faecalis. J Dent 47: 18-22, 2016.
Hashimoto M, Yamaguchi S, Sasaki JI, Kawai K, Kawakami H, Iwasaki Y, Imazato S. Inhibition of matrix metalloproteases and toxicity of gold and platinum nanoparticles in L929 fibroblast cells. Eur J Oral Sci 124(1): 68-74, 2016.
Hashimoto M, Sasaki JI, Imazato S. Investigation of the cytotoxicity of aluminum oxide nano particles and nano wires and their localization in L929 fibroblasts and RAW264 macrophages. J Biomed Mater Res B Appl Biomater 104(2): 241-52, 2016.
Hashimoto M, Kawai K, Kawakami H, Imazato S. Matrix metalloproteases inhibition and biocompatibility of gold and platinum nanoparticles. J Biomed Mater Res A 104(1): 209-17, 2016.


Xiong Y, Huang SH, Shinno Y, Furuya Y, Imazato S, Fok A, Hayashi M. The use of a fiber sleeve to improve fracture strength of pulp less teeth with flared root canals. Dent Mater 31(12): 1427-34, 2015.
Takeda K, Kitagawa H, Tsuboi R, Kiba W, Sasaki JI, Hayashi M, Imazato S. Effectiveness of non-biodegradable poly(2-hydroxyethyl methacrylate)-based hydrogel particles as a fibroblast growth factor-2 releasing carrier. Dent Mater 31(11): 1406-14, 2015.
Hashimoto M, Yamaguchi S, Imazato S. Nanoleakage and durability of resin/dentin bonds. Curr Oral Health Rep 2: 195-201, 2015.
Sasaki JI, Hashimoto M, Yamaguchi S, Itoh Y, Yoshimoto I, Matsumoto T, Imazato S. Fabrication of biomimetic bone tissue using mesenchymal stem cell-derived three-dimensional constructs incorporating endothelial cells. PLoS One 10(6): e0129266, 2015.
Hashimoto M, Sasaki J, Yamaguchi S, Kawai K, Kawakami H, Iwasaki Y, Imazato S. Gold nanoparticles inhibit matrix metalloproteases without cytotoxiciy. J Dent Res 94(8): 1085-1091, 2015.
Hirata R, Silveira L, Bonfante E, Yamaguchi S, Coelho PG, Imazato S. Effect of the diamond-like carbon coating on reliability of implant-supported crowns. Int J Oral Maxillofac Impants 30(4): 806-813, 2015.
Hashimoto M, Imazato S. Cytotoxic and genotoxic characterization of aluminum and silicon oxide nanoparticles in macrophages. Dent Mater 31(5): 556-564, 2015.
Yamamoto H, Wu X, Nakanishi H, Yamamoto Y, Uemura M, Hata T, Nishimura J, Takemasa I, Mizushima T, Sasaki J, Imazato S, Matsuura N, Doki Y, Mori M. A glucose carbonate apatite complex exhibits in vitro and in vivo anti-tumour effects. Sci Rep 5: 7742, 2015.
Tezverqil-Mutluay A, Aqee KA, Mazzoni A, Carvalho RM, Carrilho M, Tersariol IL, Nascimento FD, Imazato S, Tjaderhane L, Breschi L, Tay FR, Pashley DH. Can quaternary ammonium methacrylates inhibit matrix MMPs and cathepsins?. Dent Mater 31(2): e25-32, 2015.
Cobanoglu N, Ozer F, Imazato S. Histopathological evaluation of human pulp response to two self-etching resins. J Restorative Dent 3(1): 1-7, 2015.
Sathi G, Kenmizaki K, Yamaguchi S, Yoshida Y, Matsugaki A, Ichimoto T, Imazato S, Nakano T, Matsumoto T. Early initiation of endochondral ossification of mouse femur cultured in hydrogel with different mechanical stiffness. Tissue Eng Part C 21(6): 567-75, 2015.


Yamaguchi S, Coelho PG, Thompson VP, Tovar N, Yamauchi J, Imazato S. Dynamic finite element analysis and moving particle simulation of human enamel on a micro scale. Comput Biol Med 55: 53-60, 2014.
Yamaguchi S, Satake K, Yamaji Y, Chen YW, Tanaka TH. Three-dimensional semiautomatic liver segmentation method for non-contrast computed tomography based on a correlation map of loco regional histogram and probabilistic atlas. Comput Biol Med 55: 79-85, 2014.
Galli S, Jimbo R, Tovar N, Yoo DY, Anchieta RB, Yamaguchi S, Coelho PG. The effect of osteotomy dimension on osseointegration to resorbable media-treated implants: A study in the sheep. J Biomater Appl 29(8): 1068-74, 2014.
Hayashi M, Haapasalo M, Imazato S, Lee JI, Momoi Y, Murakami S, Whelton H, Wilson N. Dentistry in the 21st century: challenges of a globalizing world. Int Dent J 64(6): 333-342, 2014.
Kitagawa R, Kitagawa H, Izutani N, Hirose N, Hayashi M, Imazato S. Development of an antibacterial root canal filling system containing MDPB. J Dent Res 93(12): 1277-1282, 2014.
Yamaguchi S, Tsutsui K, Satake K, Morikawa S, Shirai Y, Tanaka HT. Dynamic analysis of a needle insertion for soft materials: Arbitrary Lagrangian-Eulerian-based three-dimensional finite element analysis. Comput Biol Med 53: 42-47, 2014.
Cobanoglu N, Ozer F, Demirci M, Erganis O, Imazato S. Bacterial penetration of restored cavities using two self-etching bonding systems. Eur J Dent 8(2): 166-171, 2014.
Kitagawa H, Takeda K, Kitagawa R, Izutani N, Miki S, Hirose N, Hayashi M, Imazato S. Development of sustained antimicrobial-release systems using poly-HEMA/TMPT hydrogels. Acta Biomater 10(10): 4285-4295, 2014.
Iijima M, Hashimoto M, Nakagaki S, Muguruma T, Kohda N, Endo K, Mizoguchi I. Bioactive glass coating of orthodontic material for the recovery of mechanical properties of etched enamel. J Biomater Tissue Eng 4(4): 274-280, 2014.
Hashimoto M, Toshima H, Yonezawa T, Kawai K, Iijima M, Endo K. Evaluation of silver nano particle toxicity to RAW264.7 cells in a three-dimensional cell culture. J Biomater Tissue Eng 4(1): 51-58, 2014.
Yamanishi Y, Yamaguchi S, Imazato S, Nakano T, Yatani H. Effects on the implant design on peri-implant bone stress and abutment micro movement: three-dimensional finite element analysis of original computer-aided design models. J Periodontol 85(9): e333-e338, 2014.
Sasaki JI, Matsumoto T, Imazato S. Oriented bone formation using biomimetic fibrin hydrogels with three-dimensional patterned bone matrices. J Biomed Mater Res A 103(2): 622-627, 2014.
Egusa H, Kayashima H, Miura J, Uraguchi S, Wang F, Okawa H, Sasaki JI, Saeki M, Matsumoto T, Yatani H. Comparative Analysis of Mouse Induced Pluripotent Stem Cells and Mesenchymal Stem Cells during Osteogenic Differentiation in vitro. Stem Cells Dev 23(18): 2156-2169, 2014.
Kakino K, Endo K, Hashimoto M, Furuta K, Ohno H. Visualization study on distortion of metal frame by polymerization shrinkage and thermal contraction of resin. Dent Mater J 33(1): 118-24, 2014.
Kaga M, Kakuda S, Ida Y, Toshima H, Hashimoto M, Endo K, Sano H. Inhibition of enamel demineralization by buffering effect of S-PRG filler-containing dental sealant. Eur J Oral Sci 122(1): 78-83, 2014.

Imazato S, Ma S, Chen JH, Xu HH. Therapeutic polymers for dental adhesives: Loading resins with bio-active components. Dent Mater 30: 97-104, 2014.


Ma S, Imazato S, Takahashi Y, Kiba W, Takeda K, Izutani N, Kitagawa H, Chen J. Mechanism of detoxification of the cationic antibacterial monomer 12-methacryloyloxydodecylpyridiniumbromide (MDPB) by N-acetyl cysteine. Dent Mater 29(12): 1219-1227, 2013.
Yamaguchi S, Yoshida Y, Noborio H, Murakami S, Imazato S. The usefulness of a haptic virtual reality simulator with repetitive training to teach caries removal and periodontal pocket probing skills. Dent Mater J 32(5): 847-852, 2013.
Iijima M, Hashimoto M, Kohda N, Nakagaki S, Muguruma T, Endo K, Mizoguchi I. Crystal growth on bioactive glass sputter-coated alumina in artificial saliva. Dent Mater J 32(5): 775-780, 2013.
Hashimoto M, Toshima H, Yonezawa T, Kawai K, Narushima T, Kaga M, Endo K. Micromorphological cellular responses of MC3T3-E1 and RAW264.7 after exposure to water-dispersible silver nanoparticles stabilized by metal-carbon o-bonds. Dent Mater J 32(5): 1-9, 2013.
Inaba Y, Teraoka F, Nakagawa M, Imazato S. Development of a new direct core build-up method using a hollow fiber-reinforced post. Dent Mater J 32(5): 718-724, 2013.
Machado LS, Bonfante EA, Anchieta RB, Yamaguchi S, Coelho PG. Implant-Abutment Connection Designs for Anterior Crowns: Reliability and Failure Modes. Implant Dent 22(5): 540-545, 2013.
Brambilla E, Ionescu A, Fadini L, Mazzoni A, Imazato S, Pashley D, Breschi L, Gagliani M. Influence of MDPB-containing Primer on Streptococcus Mutans Biofilm Formation in Simulated Class I Restorations. J Adhes Dent 15(5): 431-438, 2013.
Zhang K, Li F, Imazato S, Cheng L, Liu H, Arola DD, Bai Y, Xu HH. Dual antibacterial agents of nano-silver and 12-methacryloxydodecylpyridinium bromide in dental adhesive to inhibit caries. J Biomed Mater Res B Appl Biomater 101(6): 929-938, 2013.
Zhang K, Cheng L, Imazato S, Antonucci JM, Lin NJ, Lin-Gibson S, Bai Y, Xu HH. Effects of dual antibacterial agents MDPB and nano-silver in primer on microcosm biofilm, cytotoxicity and dentine bond properties. J Dent 41(5): 464-474, 2013.
Matsushita-Tokugawa M, Miura J, Iwami Y, Sakagami T, Izumi Y, Mori N, Hayashi M, Imazato S, Takeshige F, Ebisu S. Detection of dentinal microcracks using infrared thermography. J Endod 39(1): 88-91, 2013.
Egusa H, Kobayashi M, Matsumoto T, Sasaki JI, Uraguchi S, Yatani H. Application of cyclic strain for accelerated skeletal myogenic differentiation of mouse bone marrow-derived mesenchymal stromal cells with cell alignment. Tissue Eng Part A 19(5-6): 770-782, 2013.
Yoshioka S, Takahashi Y, Abe M, Michikami I, Imazato S, Wakisaka S, Hayashi M, Ebisu S. Activation of the Wnt/β-catenin pathway and tissue inhibitor of metalloprotease I during tertiary dentinogenesis. J Biochem 153(1): 43-50, 2013.
Ono S, Yamaguchi S, Kusumoto N, Nakano T, Sohmura T, Yatani H. Optical impression method to measure three-dimensional position and orientation of dental implants using an optical tracker. Clin Oral Implants Res 24(10): 1117-22, 2013.

今里 聡. バイオアクティブ機能性材料としてのS-PRGフィラー:その抗菌性について.クイントデンタルアドクロニクル, 82-86, 2013.
佐々木淳一,今里 聡.歯髄再生技術はここまで進化した 第1回:歯由来の細胞を用いた歯髄再生の試み.日本歯科評論 73(10): 153-155, 2013.
佐々木淳一,今里 聡.歯髄再生技術はここまで進化した 第2回:歯由来以外の細胞を用いた歯髄再生の試み.日本歯科評論 73(11): 145-147, 2013
佐々木淳一,今里 聡.歯髄再生技術はここまで進化した 第3回:成長因子やスキャフォールドの応用.日本歯科評論 73(12): 141-143, 2013.

今里 聡 監修.削るう蝕,削らないう蝕.クインテッセンス出版,東京都,全215ページ,2013年発行.


Yamaguchi S, Yamada Y, Yoshida Y, Noborio H, Imazato S. Development of three-dimensional patient face model that enables real-time collision detection and cutting operation for a dental simulator. Dent Mater J 31(6): 1047-1053, 2012.
Ma S, Imazato S, Chen J-H, Mayanagi G, Takahashi N, Ishimoto T, Nakano T. Effects of a coating resin containing S-PRG filler to prevent demineralization of root surfaces. Dent Mater J 31(6): 909-915, 2012.
An SH, Matsumoto T, Miyajima H, Nakahira A, Kim KH, Imazato S. Porous zirconia/hydroxyapatite scaffolds for bone reconstruction. Dent Mater 28(12): 1221-1231, 2012.
Yamanishi Y, Yamaguchi S, Imazato S, Nakano T, Yatani H. Influences of implant neck design and implant-abutment joint type on peri-implant bone stress and abutment micromovement; Three-dimensional finite element analysis. Dent Mater 28(11): 1126-1133, 2012.
Sasaki JI, Matsumoto T, Egusa H, Matsusaki M, Nishiguchi A, Nakano T, Akashi M, Imazato S, Yatani H. In vitro reproduction of endochondral ossification using 3D mesenchymal stem cell construct. Integrative Biology 4(10): 1207-1214, 2012.
Xin WU, Nakagawa M, Teraoka F. Failure morphology of all-ceramic prostheses. Dent Mater 31(3): e494-498, 2012.
Ma S, Izutani N, Imazato S, Chen JH, Kiba W, Yoshikawa R, Takeda K, Kitagawa H, Ebisu S. Assessment of bactericidal effects of quaternary ammonium-based antibacterial monomers in combination with colloidal platinum nanoparticles. Dent Mater J 31(1): 150-156, 2012.
Ogawa T, Ikebe K, Murai S, Enoki K, Maeda Y, Imazato S, Ebisu S. Clinically-acceptable restoration may be a hotbed for cariogenic microbes. Gerodontology 29(2): e845-850, 2012.
An SH, Matsumoto T, Sasaki JI, Miyajima H, Narayanan R, Imazato S, Kim KH. In vitro bioactivity evaluation of nano- and micro-crystaline anodic TiO2; HA formation, cellular affinity and organ culture. Mater Sci Eng C 32(8): 2516-2522, 2012.
An SH, Matsumoto T, Miyajima H, Sasaki JI, Narayanan R, Kim KH. Surface characterization of alkali- and heat-treated Ti with or without prior acid etching. Applied Surface Science 258(10): 4377-4382, 2012.
Momoi Y, Hayashi M, Fujitani M, Fukushima M, Imazato S, Kubo S, Nikaido T, Shimizu A, Unemori M, Yamaki C. Clinical guidelines for treating caries in adults following a minimal intervention policy - Evidence and consensus based report -. J Dent 40(2): 95-105, 2012.

今里 聡. 根面う蝕の再石灰化. 日本歯科理工学会誌 31: 217-220, 2012.
今里 聡. 抗菌性レジンモノマーによる感染制御を利用した修復治療. 日本歯科医師会雑誌 65: 275-281, 2012.

Imazato S, Chen J-H, Ma S, Izutani N, Li F. Antibacterial resin monomers based on quaternary ammonium and their benefits in restorative dentistry. Japanese Dental Science Review 48(2): 115-125, 2012.
Imazato S. Dental restorative materials in the new era: A shift to restoratives with “bio-protective” & “bio-promoting” effects. J Osaka Univ Dent Soc 56(2): 113-118, 2012.

Imazato S. Bio-active bonding with an adhesive containing the antibacterial monomer MDPB. In At the Forefront -Illustrated topics in dental research and clinical practice- (Yoshie H, ed.), Quintessence Publishing Co, Inc, USA, 61-64, 2012.


Kusdemir M, Gunal S, Özer F, Imazato S, Izutani N, Ebisu S, Blatz MB. Evaluation of cytotoxic effects of six self-etching adhesives with direct and indirect contact tests. Dent Mater J 30(6): 799-805, 2011.
Matsumoto TJ, An SH, Ishimoto T, Nakano T, Matsumoto T, Imazato S. Zirconia-hydroxyapatite composite material with micro porous structure. Dent Mater 27(11): e205-212, 2011.
Rolland SL, McCabe JF, Imazato S, Walls AWG. A randomised trial comparing the antibacterial effects of dentine primers against bacteria in natural root caries. Caries Res 45(6): 574-580, 2011.
Izutani N, Imazato S, Nakajo K, Takahashi N, Takahashi Y, Ebisu S, Russell RRB. Effects of the antibacterial monomer 12-methacryloyloxydodecylpyridinium bromide (MDPB) on bacterial viability and metabolism. Eur J Oral Sci 119(2): 175-181, 2011.
Tezvergil-Mutluay A, Agee KA, UchiyamaT, Imazato S, Mutluay MM, Cadenaro M, Breschi L, Nishitani Y, Tay FR, Pashley DH. The inhibitory effects of quaternary ammonium methacrylates on soluble and matrix-bound MMPs. J Dent Res 90(4): 535-540, 2011.
Pennington M, Heasman P, Gaunt F, Güntsch A, Ivanovski S, Imazato S, Rajapakse S, Allen E, Flemmig T, Sanz M, Vernazza C. The cost-effectiveness of supportive periodontal care: a global perspective. J Clin Periodontol 38(6): 535-561, 2011.
Miyajima H, Matsumoto T, Sakai T, Yamaguchi S, Abe M, Wakisaka S, An S-H, Lee K-Y, Egusa H, Imazato S. Hydrogel-based biomimetic environment for in vitro modulation of branching morphogenesis. Biomaterials 32(28): 6754-6763, 2011.
Yoshida Y, Yamaguchi S, Kawamoto Y, Noborio H, Murakami S, Sohmura T. Development of a multi-layered virtual tooth model for the haptic dental training system. Dent Mater J 30(1): 1-6, 2011.
An SH, Narayanan R, Matsumoto T, Lee HJ, Kwon TY, Kim KH. Crystallinity of anodic TiO2 nanotubes and bioactivity. J Nanosci Nanotec 11(6): 4910-4918, 2011.

山口 哲,今里 聡.材料特性からみたコンポジットレジンの現状.歯界展望 118: 992-997, 2011.

Pashley DH, Tay FR, Imazato S. How to increase the durability of resin-dentin bonds. Compend Contin Educ Dent 32: 60-64, 2011.

Yamaguchi S, Ohtani T, Ono S, Yamanishi Y, Sohmura T, Yatani H. Intuitive Surgical Navigation System for Dental Implantology by using Retinal Imaging Display, In Implant Dentistry - A Rapidly Evolving Practice. (Ilser T, ed), InTech, Croatia, 301-316, 2011.